Learning produces a hippocampal cognitive map in the form of an orthogonalized state machine
Cognitive maps confer animals with flexible intelligence by representing spatial, temporal,
and abstract relationships that can be used to shape thought, planning, and behavior …
and abstract relationships that can be used to shape thought, planning, and behavior …
Transformer as a hippocampal memory consolidation model based on NMDAR-inspired nonlinearity
The hippocampus plays a critical role in learning, memory, and spatial representation,
processes that depend on the NMDA receptor (NMDAR). Inspired by recent findings that …
processes that depend on the NMDA receptor (NMDAR). Inspired by recent findings that …
[HTML][HTML] Beyond correlation: optimal transport metrics for characterizing representational stability and remapping in neurons encoding spatial memory
Introduction Spatial representations in the entorhinal cortex (EC) and hippocampus (HPC)
are fundamental to cognitive functions like navigation and memory. These representations …
are fundamental to cognitive functions like navigation and memory. These representations …
[HTML][HTML] Calcium imaging reveals fast tuning dynamics of hippocampal place cells and CA1 population activity during free exploration task in mice
Hippocampal place cells are a well-known object in neuroscience, but their place field
formation in the first moments of navigating in a novel environment remains an ill-defined …
formation in the first moments of navigating in a novel environment remains an ill-defined …
[HTML][HTML] Estimating neuronal firing density: A quantitative analysis of firing rate map algorithms
RM Grieves - PLOS Computational Biology, 2023 - journals.plos.org
The analysis of neurons that exhibit receptive fields dependent on an organism's spatial
location, such as grid, place or boundary cells typically begins by mapping their activity in …
location, such as grid, place or boundary cells typically begins by mapping their activity in …
[HTML][HTML] BTSP, not STDP, Drives Shifts in Hippocampal Representations During Familiarization
Synaptic plasticity is widely thought to support memory storage in the brain, but the rules
determining impactful synaptic changes in-vivo are not known. We considered the trial-by …
determining impactful synaptic changes in-vivo are not known. We considered the trial-by …
Insights in neuronal tuning: Navigating the statistical challenges of autocorrelation and missing variables
F Nevjen, B Dunn - bioRxiv, 2023 - biorxiv.org
Recent advances in neuroscience have improved our ability to investigate neural activity by
making it possible to measure vast amounts of neurons and behavioral variables, and …
making it possible to measure vast amounts of neurons and behavioral variables, and …
[HTML][HTML] Hippocampal sequences span experience relative to rewards
Hippocampal place cells fire in sequences that span spatial environments and non-spatial
modalities, suggesting that hippocampal activity can anchor to the most behaviorally salient …
modalities, suggesting that hippocampal activity can anchor to the most behaviorally salient …
Disorganized Inhibitory Dynamics and Functional Connectivity in Hippocampal area CA1 of 22q11. 2 Deletion Mutant Mice
Individuals with the 22q11. 2 deletion syndrome, one of the strongest genetic risk factors for
schizophrenia, demonstrate cognitive impairments such as episodic memory dysfunction …
schizophrenia, demonstrate cognitive impairments such as episodic memory dysfunction …
[HTML][HTML] Tracking longitudinal population dynamics of single neuronal calcium signal using SCOUT
In vivo calcium imaging enables simultaneous recording of large neuronal ensembles
engaged in complex operations. Many experiments require monitoring and identification of …
engaged in complex operations. Many experiments require monitoring and identification of …