Opportunities and challenges for co-delivery nanomedicines based on combination of phytochemicals with chemotherapeutic drugs in cancer treatment

Q Gao, J Feng, W Liu, C Wen, Y Wu, Q Liao… - Advanced drug delivery …, 2022 - Elsevier
The therapeutic limitations such as insufficient efficacy, drug resistance, metastasis, and
undesirable side effects are frequently caused by the long duration monotherapy based on …

The role of polyphenols in overcoming cancer drug resistance: A comprehensive review

P Maleki Dana, F Sadoughi, Z Asemi… - Cellular & molecular …, 2022 - Springer
Chemotherapeutic drugs are used to treat advanced stages of cancer or following surgery.
However, cancers often develop resistance against drugs, leading to failure of treatment and …

Effects and mechanisms of curcumin for the prevention and management of cancers: An updated review

ZJ Yang, SY Huang, DD Zhou, RG Xiong, CN Zhao… - Antioxidants, 2022 - mdpi.com
Cancer is the leading cause of death in the world. Curcumin is the main ingredient in
turmeric (Curcuma longa L.), and is widely used in the food industry. It shows anticancer …

Curcumin and colorectal cancer: An update and current perspective on this natural medicine

W Weng, A Goel - Seminars in cancer biology, 2022 - Elsevier
Colorectal cancer (CRC) is one of most common malignancies worldwide and its incidence
is still growing. In spite of recent advances in targeted therapies, their clinical efficacy has …

Research status and molecular mechanism of the traditional Chinese medicine and antitumor therapy combined strategy based on tumor microenvironment

Y Zhang, Y Lou, J Wang, C Yu, W Shen - Frontiers in immunology, 2021 - frontiersin.org
Treatment of malignant tumors encompasses multidisciplinary comprehensive diagnosis
and treatment and reasonable combination and arrangement of multidisciplinary treatment …

[HTML][HTML] Unraveling the function of epithelial-mesenchymal transition (EMT) in colorectal cancer: Metastasis, therapy response, and revisiting molecular pathways

E Sabouni, MM Nejad, S Mojtabavi… - Biomedicine & …, 2023 - Elsevier
Colorectal cancer (CRC) is a dangerous form of cancer that affects the gastrointestinal tract.
It is a major global health concern, and the aggressive behavior of tumor cells makes it …

Plant-derived bioactive compounds in colorectal cancer: Insights from combined regimens with conventional chemotherapy to overcome drug-resistance

LI Gavrilas, D Cruceriu, A Mocan, F Loghin, D Miere… - Biomedicines, 2022 - mdpi.com
Acquired drug resistance represents a major clinical problem and one of the biggest
limitations of chemotherapeutic regimens in colorectal cancer. Combination regimens using …

Natural polyphenols for treatment of colorectal cancer

Y Zhang, K Liu, C Yan, Y Yin, S He, L Qiu, G Li - Molecules, 2022 - mdpi.com
Colorectal cancer (CRC) is a prevalent and serious gastrointestinal malignancy with high
mortality and morbidity. Chemoprevention refers to a newly emerged strategy that uses …

Natural products in preventing tumor drug resistance and related signaling pathways

C Yang, Z Mai, C Liu, S Yin, Y Cai, C Xia - Molecules, 2022 - mdpi.com
Drug resistance is still an obstacle in cancer therapy, leading to the failure of tumor
treatment. The emergence of tumor drug resistance has always been a main concern of …

Curcumin, calebin A and chemosensitization: How are they linked to colorectal cancer?

A Brockmueller, SM Samuel, A Mazurakova… - Life Sciences, 2023 - Elsevier
Colorectal cancer (CRC) is one of the leading malignant diseases worldwide with a high
rate of metastasis and poor prognosis. Treatment options include surgery, which is usually …