Different neuroplastic processes can occur along the nociceptive pathways and may be
important in the transition from acute to chronic pain and for diagnosis and development of …

The nature of the transition from acute to chronic pain still eludes explanation, but chronic
pain resulting from surgery provides a natural experiment that invites clinical …

Nonspecific chronic low back pain (CLBP) is a common clinical condition that has impacts at
both the individual and societal level. Pain intensity is a primary outcome used in clinical …

Opioid use for pain management has dramatically increased, with little assessment of
potential pathophysiological consequences for the primary pain condition. Here, a short …

Background: The pathophysiology of pain involves complex nervous system interactions
after initial noxious stimuli. When stimuli persist, biochemical and structural changes occur in …

Nonpharmacological treatment strategies for acute musculoskeletal injury revolve around
pain reduction and promotion of healing in order to facilitate a return to normal function and …

Pain management in veterinary patients is a crucial component of appropriate patient care.
Multimodal analgesia that includes both systemically and locally/regionally administered …

The focus of perioperative pain management should be to attempt to minimise the
nociceptive input and reduce the risk of transition to central sensitisation. Gabapentinoids …

Abstract Purpose of Review The development of acute to chronic pain involves distinct
pathophysiological changes in the peripheral and central nervous systems. This article …

Prescription opioid misuse and addiction among chronic pain patients are emerging public
health concerns of considerable significance. Estimates suggest that more than 10% of …