Circulating tumor HPV DNA for surveillance of HPV-positive oropharyngeal squamous cell carcinoma: a narrative review

KAL Kuhs, JC Brenner, FC Holsinger… - JAMA oncology, 2023 - jamanetwork.com
Importance Human papillomavirus (HPV)–positive oropharyngeal squamous cell carcinoma
has an overall favorable prognosis, yet a subset of patients will experience devastating …

Recent advances in head and neck surgical oncology

A Ritter, H Levyn, J Shah - Journal of Surgical Oncology, 2024 - Wiley Online Library
In recent years, the field of head and neck oncology has witnessed a remarkable
transformation with unprecedented advances that have revolutionized the management of …

Preoperative Circulating Tumor HPV DNA and Oropharyngeal Squamous Cell Disease

D Lam, NR Sangal, A Aggarwal… - … –Head & Neck …, 2024 - jamanetwork.com
Importance The utility of preoperative circulating tumor tissue-modified viral human
papillomavirus DNA (TTMV-HPV DNA) levels in predicting human papillomavirus (HPV) …

De-Escalated Therapy and Early Treatment of Recurrences in HPV-Associated Head and Neck Cancer: The Potential for Biomarkers to Revolutionize Personalized …

WG Yarbrough, TP Schrank, BA Burtness, N Issaeva - Viruses, 2024 - mdpi.com
Human papillomavirus-associated (HPV+) head and neck squamous cell carcinoma
(HNSCC) is the most common HPV-associated cancer in the United States, with a rapid …

Circulating Human Papillomavirus Tumor DNA—Ready for Prime Time?

MN Lango - JAMA Otolaryngology–Head & Neck Surgery, 2023 - jamanetwork.com
The detection of cell-free tumor DNA fragments shed into the circulation, reflecting the
mutational landscape of a tumor type, has transformed the management of many cancers …

Reappraisal of p16 for Determining HPV Status of Head and Neck Carcinomas Arising in HPV Hotspots

S Bhardwaj, M Gitman, JD Ramirez… - The American Journal …, 2024 - journals.lww.com
In an era of head and neck oncology where HPV status will soon dictate patient
management, reliable HPV detection is critical. P16 immunohistochemistry (IHC) is currently …

Current and Emerging Diagnostic, Prognostic, and Predictive Biomarkers in Head and Neck Cancer

HW Eberly, BY Sciscent, FJ Lorenz, EM Rettig, N Goyal - Biomedicines, 2024 - mdpi.com
Head and neck cancers (HNC) are a biologically diverse set of cancers that are responsible
for over 660,000 new diagnoses each year. Current therapies for HNC require a …

Circulating Tumor HPV DNA in Patients With Head and Neck Carcinoma: Correlation With HPV Genotyping

K Mijares, R Ferrandino, R Chai, S Roof… - The American Journal …, 2024 - journals.lww.com
Circulating tumor human papillomavirus DNA (ctHPVDNA) testing using digital-droplet
polymerase chain reaction (PCR) detects fragments of tumor-modified human …

Evaluating human papillomavirus testing, prevalence, and association with prognosis in head and neck squamous cell carcinoma by subsite: A national cancer …

J Barlow, S Gilja, RM Ferrandino, MH Berger… - American Journal of …, 2024 - Elsevier
Purpose To compare human papillomavirus (HPV) testing, prevalence, and association with
prognosis between head and neck squamous cell carcinoma (HNSCC) subsites. Materials …

Liquid Biopsies for Head and Neck Cancers—Any Hope for Human Papillomavirus–Negative Disease?

JD Smith, MJ Brenner, SB Chinn - JAMA Otolaryngology–Head & …, 2024 - jamanetwork.com
To the Editor Ferrandino et al1 report clinical performance of plasma tumor tissue–modified
viral (TTMV)-human papillomavirus (HPV) DNA in diagnosis and surveillance of HPV …