A supramolecular host-guest interaction-mediated injectable hydrogel system with enhanced stability and sustained protein release

SY Lee, SI Jeon, SB Sim, Y Byun, CH Ahn - Acta Biomaterialia, 2021 - Elsevier
Injectable hydrogels have been studied as drug delivery systems because of their minimal
invasiveness and sustained drug release properties. Pluronic F127, consisting of poly …

Multifunctional supramolecular hydrogel for prevention of epidural adhesion after laminectomy

Y Wang, L Li, Y Ma, Y Tang, Y Zhao, Z Li, W Pu… - ACS …, 2020 - ACS Publications
Postoperative epidural adhesion remains a clinically challenging problem in spine surgery.
Currently there are no effective and safe antifibrotic and antiadhesion biomaterials that have …

[HTML][HTML] Superparamagnetic iron oxide nanoparticles dispersed in Pluronic F127 hydrogel: potential uses in topical applications

LC Gonçalves, AB Seabra, MT Pelegrino… - RSC …, 2017 - pubs.rsc.org
The present study is focused on the synthesis and characterization of nitric oxide (NO)-
releasing superparamagnetic iron oxide nanoparticles (Fe3O4 NPs), and their incorporation …

A tissue-adhesive F127 hydrogel delivers antioxidative copper-selenide nanoparticles for the treatment of dry eye disease

L Ou, Z Wu, X Hu, J Huang, Z Yi, Z Gong, H Li, K Peng… - Acta biomaterialia, 2024 - Elsevier
Dry eye disease (DED) is currently the most prevalent condition seen in ophthalmology
outpatient clinics, representing a significant public health issue. The onset and progression …

Polymeric micelles targeted against CD44v6 receptor increase niclosamide efficacy against colorectal cancer stem cells and reduce circulating tumor cells in vivo

F Andrade, D Rafael, M Vilar-Hernandez… - Journal of Controlled …, 2021 - Elsevier
Colorectal cancer (CRC) is a highly prevalent disease worldwide. Patient survival is
hampered by tumor relapse and the appearance of drug-resistant metastases, which are …

[HTML][HTML] Pluronic F-127 hydrogels containing copper oxide nanoparticles and a nitric oxide donor to treat skin cancer

FV Cabral, BM Santana, CN Lange, BL Batista… - Pharmaceutics, 2023 - mdpi.com
Melanoma is a serious and aggressive type of skin cancer with growing incidence, and it is
the leading cause of death among those affected by this disease. Although surgical …

Injectability of biosynthetic hydrogels: consideration for minimally invasive surgical procedures and 3D bioprinting

T Birman, D Seliktar - Advanced Functional Materials, 2021 - Wiley Online Library
Injectable hydrogels are often preferred when designing carriers for cell therapy or
developing new bio‐ink formulations. Biosynthetic hydrogels, which are a class of materials …

The recent advancement in the chitosan-based thermosensitive hydrogel for tissue regeneration

A Abdollahi, A Malek-Khatabi, MS Razavi… - Journal of Drug Delivery …, 2023 - Elsevier
To date, hydrogel-based scaffolds have opened new prospects for potential applications for
drug delivery and regeneration. The novel delivery strategies such as thermo-sensitive …

A Metal‐Polyphenol‐Based Oxygen Economizer and Fenton Reaction Amplifier for Self‐Enhanced Synergistic Photothermal/Chemodynamic/Chemotherapy

H Shi, R Wang, HC Cao, HY Guo, P Pan… - Advanced …, 2023 - Wiley Online Library
To overcome the limitations of doxorubicin (DOX) chemotherapy, nanomedicines that
integrate additional photothermal therapy (PTT) and chemodynamic therapy (CDT) …

[HTML][HTML] Drug-loaded biocompatible nanocarriers embedded in poloxamer 407 hydrogels as therapeutic formulations

E Giuliano, D Paolino, M Fresta, D Cosco - Medicines, 2018 - mdpi.com
Hydrogels are three-dimensional networks of hydrophilic polymers able to absorb and retain
a considerable amount of water or biological fluid while maintaining their structure. Among …