Frailty, an age-related condition of increased vulnerability to acute endogenous or
exogenous stressors, is a key barrier to successful treatment of cancer in older people. In …

PURPOSE To update the ASCO guideline (2018) on the practical assessment and
management of age-associated vulnerabilities in older patients undergoing systemic cancer …

Background Frailty and multimorbidity among older cancer patients affect treatment
tolerance and efficacy. Comprehensive geriatric assessment and management is …

Background The effectiveness of comprehensive geriatric assessment (CGA) in improving
health outcomes in cancer settings is unclear. We evaluated whether CGA can improve …

In 2023, ASCO updated its guideline on assessment and management of vulnerabilities in
older patients undergoing chemotherapy. The update revisited recommendations from the …

Introduction Optimizing medication use is a major issue in older patients with cancer and
pharmacists are increasingly involved in their multidisciplinary care. The implementation of …

PURPOSE Geriatric assessment (GA) is a guideline-recommended approach to optimize
cancer management in older adults. We conducted a cost-utility analysis alongside the 5C …

Introduction As the population is ageing, the number of older patients with multimorbidity
including cancer continues to increase. To improve care for these patients, the European …

Introduction This systematic review aims to summarise the available literature on the effect of
geriatric assessment (multidimensional health assessment across medical, social, and …

In addition to frailty, two novel concepts have been introduced in the field of geriatrics to
capture the heterogeneous ageing process: the first is intrinsic capacity, which uses a …