[HTML][HTML] Spotlights on extracellular vesicles in hepatocellular carcinoma diagnosis and treatment: an update review

C Wang, X Zhang, J Yu, J Bu, X Gu… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC), one of the most prevalent cancers, with a high mortality
rate worldwide, seriously impairs patient health. The lack of accurate targets impedes the …

Non-coding RNA methylation modifications in hepatocellular carcinoma: interactions and potential implications

Q Shi, Q Chu, Y Zeng, X Yuan, J Wang, Y Zhang… - Cell Communication and …, 2023 - Springer
RNA methylation modification plays a crucial role as an epigenetic regulator in the
oncogenesis of hepatocellular carcinoma (HCC). Numerous studies have investigated the …

YTHDF2 Is a Therapeutic Target for HCC by Suppressing Immune Evasion and Angiogenesis Through ETV5/PD‐L1/VEGFA Axis

J Wen, L Xue, Y Wei, J Liang, W Jia, T Yong… - Advanced …, 2024 - Wiley Online Library
Abstract N6‐methyladenosine (m6A) modification orchestrates cancer formation and
progression by affecting the tumor microenvironment (TME). For hepatocellular carcinoma …

Bone-organ axes: bidirectional crosstalk

AF Deng, FX Wang, SC Wang, YZ Zhang, L Bai… - Military Medical …, 2024 - Springer
In addition to its recognized role in providing structural support, bone plays a crucial role in
maintaining the functionality and balance of various organs by secreting specific cytokines …

[HTML][HTML] Beyond boundaries: unraveling innovative approaches to combat bone-metastatic cancers

H Lan, B Wu, K Jin, Y Chen - Frontiers in Endocrinology, 2024 - frontiersin.org
Evidence demonstrated that bones, liver, and lungs are the most common metastasis sites in
some human malignancies, especially in prostate and breast cancers. Bone is the third most …

Crosstalk between m6A modification and non-coding RNAs in HCC

Z Qiu, X Yuan, X Wang, S Liu - Cellular Signalling, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths
worldwide, with high morbidity and occurrence. Although various therapeutic approaches …

Aptamer-Based Smart Targeting and Spatial Trigger–Response Drug-Delivery Systems for Anticancer Therapy

D Park, SJ Lee, JW Park - Biomedicines, 2024 - mdpi.com
In recent years, the field of drug delivery has witnessed remarkable progress, driven by the
quest for more effective and precise therapeutic interventions. Among the myriad strategies …

[HTML][HTML] Cisplatin-based miRNA delivery strategy inspired by the circCPNE1/miR-330-3p pathway for oral squamous cell carcinoma

H Fan, H Jiang, Z Yu, Y Fan, X Liang, Y Tang… - … Pharmaceutica Sinica B, 2024 - Elsevier
Circular RNAs (circRNAs) are ideal biomarkers of oral squamous cell carcinoma (OSCC)
because of their highly stable closed-loop structure, and they can act as microRNA (miRNA) …

[HTML][HTML] Exosomes derived from pulmonary metastatic sites enhance osteosarcoma lung metastasis by transferring the miR-194/215 cluster targeting MARCKS

P Yu, Y Han, L Meng, Y Tian, Z Jin, J Luo, C Han… - … Pharmaceutica Sinica B, 2024 - Elsevier
Osteosarcoma, a prevalent primary malignant bone tumor, often presents with lung
metastases, severely impacting patient survival rates. Extracellular vesicles, particularly …

[HTML][HTML] ALKBH5 在不同免疫环境中的调控作用

张晓娴, 谢锦, 费欢, 邱郑 - Bioprocess, 2023 - hanspub.org
m6A 修饰在转录后水平调控多种细胞过程, 而RNA m6A 水平受RNA 去甲基化酶ALKBH5 调节,
维持正常的生理功能的同时也促进多种人类疾病发生发展. 在这篇综述中, 我们讨论了ALKBH5 …