Exploring the Role of Staphylococcus Aureus Toxins in Atopic Dermatitis

F Seiti Yamada Yoshikawa, J Feitosa De Lima… - Toxins, 2019 - mdpi.com
Atopic dermatitis (AD) is a chronic and inflammatory skin disease with intense pruritus and
xerosis. AD pathogenesis is multifactorial, involving genetic, environmental, and …

Biological treatments in atopic dermatitis

A Montes-Torres, M Llamas-Velasco… - Journal of clinical …, 2015 - mdpi.com
Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases that
affect both children and adults with a prevalence of 30% and 10%, respectively. Even …

[HTML][HTML] L-type amino acid transporter 1 as a target for inflammatory disease and cancer immunotherapy

K Hayashi, N Anzai - Journal of Pharmacological Sciences, 2022 - Elsevier
Ingestion of amino acids is fundamental for cellular activity. Amino acids are important
components for protein synthesis but are also crucial for intracellular metabolic reactions …

Induction of psoriasis-and atopic dermatitis-like phenotypes in 3D skin equivalents with a fibroblast-derived matrix

B Morgner, J Tittelbach, C Wiegand - Scientific Reports, 2023 - nature.com
Skin homeostasis is a complex regulated process relying on the crosstalk of keratinocytes,
fibroblasts and immune cells. Imbalances of T-cell subsets and the cytokine environment …

New insights into T cells and their signature cytokines in atopic dermatitis

A Wang, N Xu Landén - IUBMB life, 2015 - Wiley Online Library
An imbalance of the adaptive immune system mediated by various T cells plays a pivotal
role in the pathogenesis of atopic dermatitis (AD). Traditionally, sustained exposure of …

IgG from Adult Atopic Dermatitis (AD) Patients Induces Nonatopic Neonatal Thymic Gamma–Delta T Cells (γδT) to Acquire IL-22/IL-17 Secretion Profile with Skin …

BO Fagundes, TR de Sousa, A Nascimento… - International Journal of …, 2022 - mdpi.com
γδT cells mature in the human thymus, and mainly produce IL-17A or IFN-γ, but can also
produce IL-22 and modulate a variety of immune responses. Here, we aimed to evaluate …

Atopic dermatitis: molecular, cellular, and clinical aspects

J Salimian, Z Salehi, A Ahmadi… - Molecular Biology …, 2022 - Springer
Atopic dermatitis (AD) is a complicated, inflammatory skin disease, which numerous genetic
and environmental factors play roles in its development. AD is categorized into different …

[PDF][PDF] Molecular mechanisms of luteolin against atopic dermatitis based on network pharmacology and in vivo experimental validation

L Tang, J Gao, X Li, X Cao, B Zhou - Drug Design, Development …, 2022 - Taylor & Francis
Purpose To undercover the underlying mechanisms of luteolin against atopic dermatitis
(AD), clinically characterized by recurrent eczematous lesions and intense itching, based on …

New therapies for atopic dermatitis: Additional treatment classes

PP Vakharia, JI Silverberg - Journal of the American Academy of …, 2018 - Elsevier
Background A wide array of miscellaneous agents is being studied for the treatment of
atopic dermatitis (AD), including targeted topical, oral systemic, and biologic agents …

Histamine and skin barrier: are histamine antagonists useful for the prevention or treatment of atopic dermatitis?

A De Benedetto, T Yoshida, S Fridy, JES Park… - Journal of clinical …, 2015 - mdpi.com
Atopic Dermatitis (AD), the most common chronic inflammatory skin disease, is
characterized by an overactive immune response to a host of environmental allergens and …