Oxidative stress-induced damage to the retinal pigment epithelium (RPE) is considered to
be a key factor in age-related macular degeneration (AMD) pathology. RPE cells are …

Hypertensive eye disease includes a spectrum of pathological changes, the most well
known being hypertensive retinopathy. Other commonly involved parts of the eye in …

The cellular mechanisms underlying hereditary photoreceptor degeneration are still poorly
understood, a problem that is exacerbated by the enormous genetic heterogeneity of this …

Adequate oxygen delivery to a tissue depends on sufficient oxygen content in arterial blood
and blood flow to the tissue. Oximetry is a technique for the assessment of blood …

With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …

Abstract Cardiovascular (CV) disease (CVD) is the main cause of death around the world,
and assessing a patient's CV risk factors (CVRF) can play a major role in its prevention …

The microcirculation plays a key role in delivering oxygen to and removing metabolic wastes
from energy-intensive retinal neurons. Microvascular changes are a hallmark feature of …

Advances in retinal imaging are enabling researchers and clinicians to make precise
noninvasive measurements of the retinal vasculature in vivo. This includes measurements of …

Although the exact pathogenetic mechanisms leading to age-related macular degeneration
(AMD) have not been clearly identified, oxidative damage in the retina and choroid due to an …

The retina, the part of the eye, translates the light signal into an electric current that can be
sent to the brain as visual information. To achieve this, the retina requires fine-tuned …