Withaferin A: From ayurvedic folk medicine to preclinical anti-cancer drug
B Hassannia, E Logie, P Vandenabeele… - Biochemical …, 2020 - Elsevier
Despite the recent successes of targeted cancer immuno-therapies, drug resistance and
disease relapse remain a huge burden in cancer patient treatment. This has fueled renewed …
disease relapse remain a huge burden in cancer patient treatment. This has fueled renewed …
Recent advances in triterpenoid pathway elucidation and engineering
S Dinday, S Ghosh - Biotechnology Advances, 2023 - Elsevier
Triterpenoids are among the most assorted class of specialized metabolites found in all the
taxa of living organisms. Triterpenoids are the leading active ingredients sourced from plant …
taxa of living organisms. Triterpenoids are the leading active ingredients sourced from plant …
Recent trends and advances of RNA interference (RNAi) to improve agricultural crops and enhance their resilience to biotic and abiotic stresses
JK Bharathi, R Anandan, LK Benjamin… - Plant Physiology and …, 2023 - Elsevier
Over the last two decades, significant advances have been made using genetic engineering
technology to modify genes from various exotic origins and introduce them into plants to …
technology to modify genes from various exotic origins and introduce them into plants to …
Exploring nature's bounty: identification of Withania somnifera as a promising source of therapeutic agents against COVID-19 by virtual screening and in silico …
Coronaviruses are etiological agents of extreme human and animal infection resulting in
abnormalities primarily in the respiratory tract. Presently, there is no defined COVID-19 …
abnormalities primarily in the respiratory tract. Presently, there is no defined COVID-19 …
Enhancement of phytosterol and triterpenoid production in plant hairy root cultures—simultaneous stimulation or competition?
A Rogowska, A Szakiel - Plants, 2021 - mdpi.com
Plant in vitro cultures, including hairy roots, can be applied for controlled production of
valuable natural products, such as triterpenoids and sterols. These compounds originate …
valuable natural products, such as triterpenoids and sterols. These compounds originate …
Endophytes of Withania somnifera modulate in planta content and the site of withanolide biosynthesis
SS Pandey, S Singh, H Pandey, M Srivastava, T Ray… - Scientific reports, 2018 - nature.com
Tissue specific biosynthesis of secondary metabolites is a distinguished feature of medicinal
plants. Withania somnifera, source of pharmaceutically important withanolides …
plants. Withania somnifera, source of pharmaceutically important withanolides …
Withaferin A: A Pleiotropic Anticancer Agent from the Indian Medicinal Plant Withania somnifera (L.) Dunal
Cancer represents the second most deadly disease and one of the most important public
health concerns worldwide. Surgery, chemotherapy, radiation therapy, and immune therapy …
health concerns worldwide. Surgery, chemotherapy, radiation therapy, and immune therapy …
[HTML][HTML] The immunomodulatory role of Withania somnifera (L.) dunal in inflammatory diseases
HH Alanazi, E Elfaki - Frontiers in Pharmacology, 2023 - frontiersin.org
Withania somnifera (L.) Dunal (Solanaceae)(also known as Ashwagandha) is a botanical
drug that has been used for centuries to treat many chronic diseases like high blood …
drug that has been used for centuries to treat many chronic diseases like high blood …
Yeast as a promising heterologous host for steroid bioproduction
S Xu, Y Li - Journal of Industrial Microbiology & Biotechnology …, 2020 - academic.oup.com
With the rapid development of synthetic biology and metabolic engineering technologies,
yeast has been generally considered as promising hosts for the bioproduction of secondary …
yeast has been generally considered as promising hosts for the bioproduction of secondary …
In perspective: Potential medicinal plant resources of Kashmir Himalayas, their domestication and cultivation for commercial exploitation
SM Jeelani, GA Rather, A Sharma, SK Lattoo - Journal of applied research …, 2018 - Elsevier
The rich biodiversity of India and its extensive use since millennia for overall healthcare
system has found renewed interest due to recent advances in modern biology …
system has found renewed interest due to recent advances in modern biology …