Introduction Hydroxymethylglutaryl-coenzyme A reductase inhibitors (statins) lower
cholesterol synthesis in patients with hypercholesterolemia. Increased statin exposure is an …

Familial hypercholesterolaemia (FH) is a dominantly inherited disorder present from birth
that markedly elevates plasma low-density lipoprotein (LDL) cholesterol and causes …

The recommendations listed in this document are, whenever possible, evidence based.
Writing group members performed these relevant supplemental literature searches with key …

A n D GUID eLIneS affordability may often dictate which medications may be prescribed.
Patients who have exhausted prescription drug coverage or who are uninsured may require …

The Japanese Circulation Society (JCS) published the “Guidelines for elective percutaneous
coronary intervention [PCI] in patients with stable coronary disease” in 2000. In 2006 …

Introduction: Statin-induced myopathy is an important cause of statin intolerance and the
most common cause of statin discontinuation. Observational studies estimate that 10–15 …

Introduction: Statins reduce the risk of cardiovascular morbidity and mortality in patients with
or at risk for cardiovascular disease and their use is expanding, especially in elderly. Statins …

摘要背景周围神经病变是一种严重的糖尿病并发症, 在某些情况下可导致下肢丧失功能甚至截肢
. 自从他汀类药物问世以来, 其使用日益增加. 最近的报告表明他汀类药物可以影响周围神经病变 …

Background Statins are a class of medications that reduce cholesterol by inhibiting 3-
hydroxy-3-methylglutaryl-coenzyme A reductase. Whether statins can benefit patients with …

In today's society with the escalating levels of obesity, diabetes, and cardiovascular disease,
the metabolic syndrome is receiving considerable attention and is the subject of much …