[HTML][HTML] The Role of Mitochondrial Biogenesis in Ischemic Stroke

B Shademan, CB Avci, V Karamad… - Journal of Integrative …, 2023 - imrpress.com
Ischaemic stroke is a sudden neurological disorder caused by localised cerebral ischaemia
and persistent cerebral infarction. Occlusion of large arteries due to atherothrombosis …

Shenlian extract protects against ultrafine particulate matter‐aggravated myocardial ischemic injury by inhibiting inflammation response via the activation of NLRP3 …

S Qu, K Li, T Yang, Y Yang, Z Zheng… - Environmental …, 2021 - Wiley Online Library
Air pollution is a growing public health burden associated with several negative health
effects, especially cardiovascular disease. Shenlian extract (SL), a traditional Chinese …

NLRX1 increases human retinal pigment epithelial autophagy and reduces H2O2-induced oxidative stress and inflammation by suppressing FUNDC1 …

Q Wang, F He, L Wu - Allergologia et Immunopathologia, 2023 - all-imm.com
Background: Age-related macular degeneration (AMD) is a leading cause of impaired vision
as well as some earlier effects, such as reading and face recognition. Oxidative damage and …

[HTML][HTML] Cardioprotective effects of total flavonoids from Jinhe Yangxin prescription by activating the PI3K/Akt signaling pathway in myocardial ischemia injury

Y Cheng, J Tan, H Li, X Kong, Y Liu, R Guo, G Li… - Biomedicine & …, 2018 - Elsevier
The purpose of the present study was to investigate the cardioprotective effects of total
flavonoids of Jinhe yangxin prescription (JHTF) on myocardial ischemia (MI) injury rats …

Dexmedetomidine alleviates hypoxic-ischemic brain damage in neonatal rats through reducing microRNA-134-5p-mediated NLRX1 downregulation

X Guan, W Zhou, L Li, Q Peng - Journal of Stroke and Cerebrovascular …, 2022 - Elsevier
Abstract Background Dexmedetomidine (Dex) is a safe and effective anesthetic adjunct
which also has neuroprotective roles. This study aimed to validate the role of Dex in hypoxic …

Ginsenoside Rg5 attenuates hypoxia‐induced cardiomyocyte apoptosis via regulating the Akt pathway

C Wang, C Huang, J Wang, J Ye, Z Xue… - Chemical Biology & …, 2023 - Wiley Online Library
Ginsenoside Rg5 has been implicated in a variety of diseases. However, it is unknown
whether Ginsenoside Rg5 can protect against hypoxia‐induced neonatal rat cardiomyocytes …

NLRX1 Inhibits LPS-Induced Microglial Death via Inducing p62-Dependent HO-1 Expression, Inhibiting MLKL and Activating PARP-1

YL Huang, DY Huang, V Klochkov, CM Chan, YS Chen… - Antioxidants, 2024 - mdpi.com
The activation of microglia and the production of cytokines are key factors contributing to
progressive neurodegeneration. Despite the well-recognized neuronal programmed cell …

The role of inflammasome complex in ischemia‐reperfusion injury

Y Mohamadi, M Mousavi, H Khanbabaei… - Journal of Cellular …, 2023 - Wiley Online Library
Ischemia‐reperfusion injury refers to a temporary interruption of blood flow in a tissue.
Restoration of blood flow initiates the inflammation in tissue causing ischemic damage …

Pattern-Recognition Receptors and Immunometabolic Reprogramming: What We Know and What to Explore

V Kumar, JH Stewart IV - Journal of Innate Immunity, 2024 - karger.com
Background: Evolutionarily, immune response is a complex mechanism that protects the
host from internal and external threats. Pattern-recognition receptors (PRRs) recognize …

[Retracted] To Analyze the Mechanism of SalB Regulating SIRT1 to Inhibit NLRP3 and Its Ameliorative Effect on Tubulogastric Junction Tumor Lesions Complicated …

GP Wang, Z Guo - BioMed Research International, 2022 - Wiley Online Library
The objective of this research is to investigate the mediating impact of salvianolic acid B
(SalB) on SIRT1 signaling pathway and the mechanism by which it inhibits Nod‐like …