[HTML][HTML] Novel Mechanisms of Myocardial Ischemia, Ischemia-Reperfusion, and Protection by Myocardial Conditioning: Inflammasome, pyroptosis, and cytokines in …

S Toldo, AG Mauro, Z Cutter… - American Journal of …, 2018 - ncbi.nlm.nih.gov
Myocardial ischemia-reperfusion injury induces a sterile inflammatory response, leading to
further injury that contributes to the final infarct size. Locally released danger-associated …

[HTML][HTML] The scaffolding protein IQGAP1 interacts with Nucleotide Binding Domain Leucine Rich Repeat CARD containing protein (NLRC3) and inhibits type I …

AM Tocker, E Durocher, KD Jacob… - … (Baltimore, Md.: 1950 …, 2017 - ncbi.nlm.nih.gov
Sensing of cytosolic nucleotides is a critical initial step in the elaboration of type I interferon.
One of several upstream receptor cGAS (cyclic-GMP-AMP synthase) binds to cytosolic DNA …