A detailed understanding of the innate immune mechanisms involved in restricting SARS-
CoV-2 infection and how the virus disrupts these processes could reveal new strategies to …

Mutations in the SARS-CoV-2 Membrane (M) gene are relatively uncommon. The M gene
encodes the most abundant viral structural protein, and is implicated in multiple viral …

The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, is the most severe
public health event of the twenty-first century. While effective vaccines against SARS-CoV-2 …

Nucleocapsid (N) encoded by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) plays key roles in the replication cycle and is a critical serological marker. Here, we …

Nucleocapsid protein (N-protein) is required for multiple steps in betacoronaviruses
replication. SARS-CoV-2-N-protein condenses with specific viral RNAs at particular …

Inhibition of heat shock protein 90 (Hsp90), a prominent molecular chaperone, effectively
limits severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection but little is …

Biomolecular condensation, driven by multivalency, serves as a fundamental mechanism
within cells, facilitating the formation of distinct compartments, including membraneless …

In 2019, a new pandemic virus belonging to the betacoronavirus family emerged, severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This new coronavirus appeared in …

The nucleocapsid protein (N) of SARS-CoV-2 plays a pivotal role during the viral life cycle. It
is involved in RNA transcription and accounts for packaging of the large genome into virus …

Considerable progress has been made in understanding the molecular host-virus battlefield
during SARS-CoV-2 infection. Nevertheless, the assembly and egress of newly formed …