Targeted in situ cross-linking mass spectrometry and integrative modeling reveal the architectures of three proteins from SARS-CoV-2
M Slavin, J Zamel, K Zohar, T Eliyahu… - Proceedings of the …, 2021 - National Acad Sciences
Atomic structures of several proteins from the coronavirus family are still partial or
unavailable. A possible reason for this gap is the instability of these proteins outside of the …
unavailable. A possible reason for this gap is the instability of these proteins outside of the …
[HTML][HTML] Liquid-liquid phase separation of nucleocapsid proteins during SARS-CoV-2 and HIV-1 replication
BA Chau, V Chen, AW Cochrane, LJ Parent… - Cell Reports, 2023 - cell.com
The leap of retroviruses and coronaviruses from animal hosts to humans has led to two
ongoing pandemics and tens of millions of deaths worldwide. Retrovirus and coronavirus …
ongoing pandemics and tens of millions of deaths worldwide. Retrovirus and coronavirus …
LINE1-mediated reverse transcription and genomic integration of SARS-CoV-2 mRNA detected in virus-infected but not in viral mRNA-transfected cells
SARS-CoV-2 sequences can be reverse-transcribed and integrated into the genomes of
virus-infected cells by a LINE1-mediated retrotransposition mechanism. Whole-genome …
virus-infected cells by a LINE1-mediated retrotransposition mechanism. Whole-genome …
COVID-19 Biogenesis and Intracellular Transport
AA Mironov, MA Savin, GV Beznoussenko - International journal of …, 2023 - mdpi.com
SARS-CoV-2 is responsible for the COVID-19 pandemic. The structure of SARS-CoV-2 and
most of its proteins of have been deciphered. SARS-CoV-2 enters cells through the …
most of its proteins of have been deciphered. SARS-CoV-2 enters cells through the …
SARS‐CoV‐2 biology and variants: anticipation of viral evolution and what needs to be done
The global propagation of SARS‐CoV‐2 and the detection of a large number of variants,
some of which have replaced the original clade to become dominant, underscores the fact …
some of which have replaced the original clade to become dominant, underscores the fact …
Distinct motifs in the E protein are required for SARS-CoV-2 virus particle formation and lysosomal deacidification in host cells
K Miura, Y Suzuki, K Ishida, M Arakawa, H Wu… - Journal of …, 2023 - Am Soc Microbiol
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is a major public health
concern, but the mechanisms underlying its viral particle formation are not well understood …
concern, but the mechanisms underlying its viral particle formation are not well understood …
[HTML][HTML] Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets
Dissecting the evolution of memory B cells (MBCs) against SARS-CoV-2 is critical for
understanding antibody recall upon secondary exposure. Here, we used single-cell …
understanding antibody recall upon secondary exposure. Here, we used single-cell …
A 3D structural SARS-CoV-2–human interactome to explore genetic and drug perturbations
Emergence of new viral agents is driven by evolution of interactions between viral proteins
and host targets. For instance, increased infectivity of SARS-CoV-2 compared to SARS-CoV …
and host targets. For instance, increased infectivity of SARS-CoV-2 compared to SARS-CoV …
Nucleocapsid (N) gene mutations of SARS-CoV-2 can affect real-time RT-PCR diagnostic and impact false-negative results
The current COVID-19 pandemic demands massive testing by Real-time RT-PCR (Reverse
Transcription Polymerase Chain Reaction), which is considered the gold standard …
Transcription Polymerase Chain Reaction), which is considered the gold standard …
Pro-viral and anti-viral roles of the RNA-binding protein G3BP1
AK Jayabalan, DE Griffin, AKL Leung - Viruses, 2023 - mdpi.com
Viruses depend on host cellular resources to replicate. Interaction between viral and host
proteins is essential for the pathogens to ward off immune responses as well as for virus …
proteins is essential for the pathogens to ward off immune responses as well as for virus …