Epidemiology of chronic rhinosinusitis: prevalence and risk factors

AR Sedaghat, EC Kuan, GK Scadding - The Journal of Allergy and Clinical …, 2022 - Elsevier
Knowledge of chronic rhinosinusitis (CRS) epidemiology may directly impact patient care:
aiding patient identification and establishing accurate diagnosis as well as informing …

A comprehensive review of the metabolism of citrus flavonoids and their binding to bitter taste receptors

L Li, X Yan, F Chen, L Zheng, Y Hu, F He… - … Reviews in Food …, 2023 - Wiley Online Library
Citrus is an important source of flavonoids in our daily diet. Citrus flavonoids have
antioxidant, anticancer, anti‐inflammatory, and cardiovascular disease prevention functions …

Clinical role of extraoral bitter taste receptors

J Jeruzal-Świątecka, W Fendler… - International Journal of …, 2020 - mdpi.com
Humans can recognise five basic tastes: sweet, sour, salty, bitter and umami. Sour and salty
substances are linked to ion channels, while sweet, bitter and umami flavours are …

Sensory evaluation, chemical structures, and threshold concentrations of bitter-tasting compounds in common foodstuffs derived from plants and maillard reaction: A …

H Li, LF Li, ZJ Zhang, CJ Wu, SJ Yu - Critical Reviews in Food …, 2023 - Taylor & Francis
The bitterness of foodstuffs is often associated with toxicity, which negatively influences
product acceptability. However, bitter compounds have many benefits, and a slight bitter …

Bitter taste receptors: Genes, evolution and health

SP Wooding, VA Ramirez… - Evolution, Medicine, and …, 2021 - academic.oup.com
Bitter taste perception plays vital roles in animal behavior and fitness. By signaling the
presence of toxins in foods, particularly noxious defense compounds found in plants, it …

Bitter taste receptors (TAS2Rs) in human lung macrophages: receptor expression and inhibitory effects of TAS2R agonists

S Grassin-Delyle, H Salvator, N Mantov… - Frontiers in …, 2019 - frontiersin.org
Background Bitter-taste receptors (TAS2Rs) are involved in airway relaxation but are also
expressed in human blood leukocytes. We studied TAS2R expression and the effects of …

[HTML][HTML] Existing bitter medicines for fighting 2019‐nCoV‐associated infectious diseases

X Li, C Zhang, L Liu, M Gu - The FASEB Journal, 2020 - ncbi.nlm.nih.gov
The sudden outbreak of COVID‐19 has led to more than seven thousand deaths.
Unfortunately, there are no specific drugs available to cure this disease. Type 2 taste …

Proteomic analysis of nasal mucus samples of healthy patients and patients with chronic rhinosinusitis

SST Kao, A Bassiouni, M Ramezanpour… - Journal of Allergy and …, 2021 - Elsevier
Background Chronic rhinosinusitis (CRS) has a complex and multifactorial pathogenesis
with a heterogeneous inflammatory profile. Proteomic analysis of nasal mucus may enable …

Bitter taste receptors for asthma therapeutics

AP Nayak, SD Shah, JV Michael… - Frontiers in …, 2019 - frontiersin.org
Clinical management of asthma and chronic obstructive pulmonary disease (COPD) has
primarily relied on the use of beta 2 adrenergic receptor agonists (bronchodilators) and …

Airway epithelial dynamics in allergy and related chronic inflammatory airway diseases

A Laulajainen-Hongisto, SK Toppila-Salmi… - Frontiers in cell and …, 2020 - frontiersin.org
Allergic rhinitis, chronic rhinosinusitis, and asthma are highly prevalent, multifactorial chronic
airway diseases. Several environmental and genetic factors affect airway epithelial …