[HTML][HTML] Metagenomic sequencing for microbial DNA in human samples: emerging technological advances
Whole genome metagenomic sequencing is a powerful platform enabling the simultaneous
identification of all genes from entirely different kingdoms of organisms in a complex sample …
identification of all genes from entirely different kingdoms of organisms in a complex sample …
DNA methylation: shared and divergent features across eukaryotes
Chemical modification of nucleotide bases in DNA provides one mechanism for conveying
information in addition to the genetic code. 5-methylcytosine (5mC) represents the most …
information in addition to the genetic code. 5-methylcytosine (5mC) represents the most …
Evolution of DNA methylome diversity in eukaryotes
Cytosine DNA methylation (5mC) is a widespread base modification in eukaryotic genomes
with critical roles in transcriptional regulation. In recent years, our understanding of 5mC has …
with critical roles in transcriptional regulation. In recent years, our understanding of 5mC has …
[HTML][HTML] Bacterial N4-methylcytosine as an epigenetic mark in eukaryotic DNA
F Rodriguez, IA Yushenova, D DiCorpo… - Nature …, 2022 - nature.com
DNA modifications are used to regulate gene expression and defend against invading
genetic elements. In eukaryotes, modifications predominantly involve C5-methylcytosine …
genetic elements. In eukaryotes, modifications predominantly involve C5-methylcytosine …
[HTML][HTML] DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation
S Adam, H Anteneh, M Hornisch, V Wagner… - Nature …, 2020 - nature.com
DNA methylation maintenance by DNMT1 is an essential process in mammals but molecular
mechanisms connecting DNA methylation patterns and enzyme activity remain elusive …
mechanisms connecting DNA methylation patterns and enzyme activity remain elusive …
[HTML][HTML] Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods
Cytosine methylation is an ancient epigenetic modification yet its function and extent within
genomes is highly variable across eukaryotes. In mammals, methylation controls …
genomes is highly variable across eukaryotes. In mammals, methylation controls …
[PDF][PDF] Evolutionary persistence of DNA methylation for millions of years after ancient loss of a de novo methyltransferase
S Catania, PA Dumesic, H Pimentel, A Nasif… - Cell, 2020 - cell.com
Cytosine methylation of DNA is a widespread modification of DNA that plays numerous
critical roles. In the yeast Cryptococcus neoformans, CG methylation occurs in transposon …
critical roles. In the yeast Cryptococcus neoformans, CG methylation occurs in transposon …
[HTML][HTML] Genome-wide analyses of repeat-induced point mutations in the Ascomycota
S Van Wyk, BD Wingfield, L De Vos… - Frontiers in …, 2021 - frontiersin.org
The Repeat-Induced Point (RIP) mutation pathway is a fungus-specific genome defense
mechanism that mitigates the deleterious consequences of repeated genomic regions and …
mechanism that mitigates the deleterious consequences of repeated genomic regions and …
DNA hypomethylation of the host tree impairs interaction with mutualistic ectomycorrhizal fungus
J Vigneaud, A Kohler, MD Sow, A Delaunay… - New …, 2023 - Wiley Online Library
Ectomycorrhizas are an intrinsic component of tree nutrition and responses to environmental
variations. How epigenetic mechanisms might regulate these mutualistic interactions is …
variations. How epigenetic mechanisms might regulate these mutualistic interactions is …
[HTML][HTML] Epigenetic regulation of nuclear processes in fungal plant pathogens
Through the association of protein complexes to DNA, the eukaryotic nuclear genome is
broadly organized into open euchromatin that is accessible for enzymes acting on DNA and …
broadly organized into open euchromatin that is accessible for enzymes acting on DNA and …