Cardiovascular diseases (CVDs) are the leading cause of premature death and disability in
humans and their incidence is on the rise globally. Given their substantial contribution …

In the mid 1960s, experimental work on molecules under screening as coronary dilators
allowed the discovery of the mechanism of calcium entry blockade by drugs later named …

Hypertension is the leading cause of death worldwide, affecting 1.4 billion people.
Treatment options include the widely used calcium channel blockers, among which …

Hypertension is a significant risk factor for cardiovascular and cerebrovascular diseases and
the leading cause of premature death worldwide. However, the pathogenesis of the …

For the first time, three phase hollow fiber liquid phase microextraction using an influential,
and green middle phase comprised a new relatively-hydrophobic deep eutectic solvent …

The prevalence of hypertension and comorbidities such as metabolic syndrome, diabetes
mellitus, and chronic kidney disease in India is alarmingly high. Amlodipine, an older …

In the initial hours following the application of the calcium channel blocker (CCB) nifedipine
to microtissues consisting of human induced pluripotent stem cell-derived cardiomyocytes …

Osteoarthritis (OA) ranks as the prevailing type of arthritis on a global scale, for which no
effective treatments are currently available. Arterial hypertension is a common comorbidity in …

Highlights•Complex and interrelated mechanisms involved in blood pressure
regulation.•Multiple molecular targets for antihypertensive peptides.•Empirical and …

Hypertension (HTN) is one of the main cardiovascular risk factors and is considered a major
public health problem. Numerous approaches have been developed to lower blood …