The TFCP2/Grainyhead family of transcription factors is divided into two distinct subfamilies,
one of which includes the Grainyhead-like 1-3 (GRHL1-3) proteins and the other consists of …

The mammalian homologs of the D. melanogaster Grainyhead gene, Grainyhead-like 1–3
(GRHL1, GRHL2 and GRHL3), are transcription factors implicated in wound healing …

Mouse embryonic stem cell (mESC) self‐renewal can be maintained by activation of the
leukaemia inhibitory factor (LIF)/signal transducer and activator of transcription 3 (Stat3) …

Abstract Epithelial-mesenchymal transition (EMT), a biological process by which polarized
epithelial cells convert into a mesenchymal phenotype, has been implicated to contribute to …

Transcription factors (TFs) play key roles in the regulation of gene expression by binding in a
sequence-specific manner to genomic DNA. In eukaryotes, DNA binding is achieved by a …

Abstract Grainyhead (Grh)/CP2 transcription factors are highly conserved in multicellular
organisms as key regulators of epithelial differentiation, organ development and skin barrier …

The Grainyhead-like (GRHL) family of transcription factors has three mammalian members,
which are currently termed Grainyhead-like 1 (GRHL1), Grainyhead-like 2 (GRHL2), and …

The transcription factor LSF (Late SV40 Factor), also known as TFCP2, belongs to the
LSF/CP2 family related to Grainyhead family of proteins and is involved in many biological …

In recent years, the TFCP2 (transcription factor cellular promoter 2)/TFCP2L1 (TFCP2-like
1)/UBP1 (upstream binding protein 1) subfamily of transcription factors has been attracting …

Abstract Grainyhead-like 2 (GRHL2), one of the three homologs of Drosophila grainyhead,
contributes to epithelial morphogenesis and differentiation. Dysregulation of GRHL2 has …