Secondary immunodeficiency related to kidney disease (SIDKD)—definition, unmet need, and mechanisms

S Steiger, J Rossaint, A Zarbock… - Journal of the American …, 2022 - journals.lww.com
Kidney disease is a known risk factor for poor outcomes of COVID-19 and many other
serious infections. Conversely, infection is the second most common cause of death in …

Renal ageing

JE Martin, MT Sheaff - The Journal of Pathology: A Journal of …, 2007 - Wiley Online Library
The function of the kidney, as well as its morphology, changes markedly with age. The
glomerular filtration rate falls progressively, independent of overt pathology. Glomerular …

Renal transplantation in elderly patients older than 70 years of age: results from the Scientific Registry of Transplant Recipients

PS Rao, RM Merion, VB Ashby, FK Port, RA Wolfe… - …, 2007 - journals.lww.com
Background. Elderly patients (ages 70 yr and older) are among the fastest-growing group
starting renal-replacement therapy in the United States. The outcomes of elderly patients …

[HTML][HTML] Post-transplant infections now exceed acute rejection as cause for hospitalization: a report of the NAPRTCS

VR Dharnidharka, DM Stablein, WE Harmon - American Journal of …, 2004 - Elsevier
Newer immunosuppressive agents have dramatically reduced the rates of acute graft
rejection (AR) over the last decade but may have exacerbated the problem of post-transplant …

Biological drugs for systemic lupus erythematosus or active lupus nephritis and rates of infectious complications. Evidence from large clinical trials

S Steiger, L Ehreiser, J Anders, HJ Anders - Frontiers in Immunology, 2022 - frontiersin.org
Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease that frequently
affects the kidneys, known as lupus nephritis (LN). Such patients are treated with …

The combination of donor and recipient age is critical in determining host immunoresponsiveness and renal transplant outcome

SG Tullius, H Tran, I Guleria, SK Malek… - Annals of …, 2010 - journals.lww.com
Objective: To evaluate the interaction of donor and recipient age on transplant outcome and
immune response. Summary Background Data: The age of donor and recipient is becoming …

Passive microwave biosensor for real-time monitoring of subsurface bacterial growth

MC Jain, AV Nadaraja, S Mohammadi… - … Circuits and Systems, 2021 - ieeexplore.ieee.org
A real-time and label-free microstrip sensor capable of detecting and monitoring subsurface
growth of Escherichia coli (E. coli) on solid growth media such as Luria-Bertani (LB) agar is …

[HTML][HTML] Solid-organ transplantation in older adults: current status and future research

M Abecassis, ND Bridges, CJ Clancy, MA Dew… - American Journal of …, 2012 - Elsevier
An increasing number of patients older than 65 years are referred for and have access to
organ transplantation, and an increasing number of older adults are donating organs …

A rationale for age-adapted immunosuppression in organ transplantation

F Krenzien, A ElKhal, M Quante, HRC Biefer… - …, 2015 - journals.lww.com
Demographic changes are associated with a steady increase of older patients with end-
stage organ failure in need for transplantation. As a result, the majority of transplant …

Risk factors for early graft failure and death after kidney transplantation in recipients older than 70 years

M Lemoine, DT Beauport, T Lobbedez… - Kidney international …, 2019 - Elsevier
Introduction Although kidney transplantation carries a survival benefit compared with
dialysis, mortality, especially the first year after transplantation, is high in recipients older …