The Role and Mechanism of the Histone Methyltransferase G9a in Tumors: Update

H Zhou, J Gui, L Zhu, Y Mi - OncoTargets and Therapy, 2024 - Taylor & Francis
Methylation-mediated gene silencing is closely related to the occurrence and development
of human tumors. The euchromatic histone lysine methyltransferase 2 (EHMT2, also known …

[HTML][HTML] EZH2/G9a interact to mediate drug resistance in non-small-cell lung cancer by regulating the SMAD4/ERK/c-Myc signaling axis

Q Zhang, Y Shi, S Liu, W Yang, H Chen, N Guo, W Sun… - Cell Reports, 2024 - cell.com
Drug resistance is the leading problem in non-small-cell lung cancer (NSCLC) therapy. The
contribution of histone methylation in mediating malignant phenotypes of NSCLC is well …

[HTML][HTML] Role and mechanism of FOXG1-related epigenetic modifications in cisplatin-induced hair cell damage

Y Mu, S Zou, M Li, Y Ding, X Huang, Z He… - Frontiers in Molecular …, 2023 - frontiersin.org
Cisplatin is widely used in clinical tumor chemotherapy but has severe ototoxic side effects,
including tinnitus and hearing damage. This study aimed to determine the molecular …