Diagnosis of hypertension—elevated blood pressure (BP) associated with increased
cardiovascular disease (CVD) risk—and its management for decades have been based …

Circadian rhythms impact cardiac and vascular pathophysiology, resulting in 24-hour
patterning of symptoms and life-threatening/ending events (chronopathology), plus kinetics …

Multiple physiological variables change over time in a predictable and repetitive manner,
guided by molecular clocks that respond to external and internal clues and are coordinated …

Background The morning blood pressure surge (MBPS) is related to an exaggerated risk of
cardiovascular diseases and mortality. With increasing attention on circadian change in …

Abstract Purpose of Review Current hypertension guidelines do not provide
recommendation on when-to-treat. Herein, we review the current evidence on ingestion-time …

Non‐dipping and nocturnal hypertension are commonly found during ABPM in pediatric
kidney transplant recipients. These entities are independently associated with increased …

Hypertension is a silent killer and is the leading preventable risk factor for premature death
and disability worldwide. 1 According to the latest US Center for Disease Control (CDC) …

Introduction Office blood pressure measurements (OBPM), still used today for diagnosis and
management of hypertension, fail to reveal clinically important features of the mostly …

The purpose of this communication is to describe the unique features of the investigative
protocols of both MAPEC and Hygia Chronotherapy Trial and to discuss in detail the …

Background: The risk of cardiovascular and cerebrovascular events is the highest during the
first several hours post-awakening in patients with hypertension. This is largely due to …