Mitophagy is an essential mitochondrial quality control mechanism that eliminates damaged
mitochondria and the production of reactive oxygen species (ROS). The relationship …

The major concept of" oxidative stress" is an excess elevated level of reactive oxygen
species (ROS) which are generated from vigorous metabolism and consumption of oxygen …

Background and Aims NAFLD and its more‐advanced form, steatohepatitis (NASH), is
associated with obesity and is an independent risk factor for cardiovascular, liver‐related …

Mitochondria play a key role in both health and disease. Their function is not limited to
energy production but serves multiple mechanisms varying from iron and calcium …

Oxidative stress develops as a response to injury and reflects a breach in the cell's
antioxidant capacity. Therefore, the fine-tuning of reactive oxygen species (ROS) generation …

Mitochondria serve as a hub for a multitude of vital cellular processes. To ensure an efficient
deployment of mitochondrial tasks, organelle homeostasis needs to be preserved …

Ischemic stroke (IS) accounts for more than 80% of the total stroke, which represents the
leading cause of mortality and disability worldwide. Cerebral ischemia/reperfusion injury …

Mitochondria are double membrane organelles in eukaryotic cells that provide energy by
generating adenosine triphosphate (ATP) through oxidative phosphorylation. They are …

As essential regulators of mitochondrial quality control, mitochondrial dynamics and
mitophagy play key roles in maintenance of metabolic health and cellular homeostasis. Here …

Mitochondria are subcellular organelles involved in essential cellular functions, including
cytosolic calcium regulation, cell apoptosis, and reactive oxygen species production. They …