Thyroglobulin (Tg) is secreted by thyroid follicular cells and stored in the thyroid follicular
lumen as a component of thyroid hormone. It is known that both benign and well …

An ever-increasing population of patients with papillary thyroid cancer is engaging with
health care systems around the world. Numerous questions about optimal management …

Controversy exists over optimal management of low-risk differentiated thyroid cancer. This
controversy occurs in all aspects of management, including surgery, use of radioactive …

The treatment of differentiated thyroid cancer continues to move away from a 'one size fits
all'approach to a process of tailored therapeutic decision-making that incorporates disease …

Context: There is much debate surrounding the choice of which patient should be submitted
to postsurgical remnant radioiodine remnant ablation (RRA), particularly in low-risk (LR) and …

Objectives To investigate the impact of the lymph node ratio (LNR) on postoperative
thyroglobulin (Tg) levels in patients with papillary thyroid carcinoma (PTC). Patients and …

IGSF1 is a membrane glycoprotein highly expressed in the anterior pituitary. Pathogenic
mutations in the IGSF1 gene (on Xq26. 2) are associated with X-linked central …

Objective Since papillary thyroid cancer (PTC) patients with pre-ablation stimulated
thyroglobulin (s-Tg)< 1 ng/mL generally have a favorable prognosis, is TSH suppression still …

Objective: In intermediate risk (IR) differentiated thyroid cancer (DTC) patients, selective use
of radioiodine (131-I) for remnant ablation and/or as adjuvant therapy (RRA) is advocated …

Purpose The diagnostic, therapeutic and health-care management protocol (Protocollo
Gestionale Diagnostico-Terapeutico-Assistenziale, PDTA) by the Association of the Italian …