Nanocrystals for Deep-Tissue In Vivo Luminescence Imaging in the Near-Infrared Region

Y Yang, Q Jiang, F Zhang - Chemical Reviews, 2023 - ACS Publications
In vivo imaging technologies have emerged as a powerful tool for both fundamental
research and clinical practice. In particular, luminescence imaging in the tissue-transparent …

Chemical technology principles for selective bioconjugation of proteins and antibodies

P Chauhan, V Ragendu, M Kumar, R Molla… - Chemical Society …, 2024 - pubs.rsc.org
Proteins are multifunctional large organic compounds that constitute an essential
component of a living system. Hence, control over their bioconjugation impacts science at …

Oxyhaemoglobin saturation NIR-IIb imaging for assessing cancer metabolism and predicting the response to immunotherapy

Z Fang, C Wang, J Yang, Z Song, C Xie, Y Ji… - Nature …, 2024 - nature.com
In vivo quantitative assessment of oxyhaemoglobin saturation (sO2) status in tumour-
associated vessels could provide insights into cancer metabolism and behaviour. Here we …

An Activatable Near‐Infrared Fluorescent Probe for Precise Detection of the Pulmonary Metastatic Tumors: A Traditional Molecule Having a Stunning Turn

Q Jia, R Zhang, H Yan, Y Feng, F Sun… - Angewandte …, 2023 - Wiley Online Library
An accurate detection of lung metastasis is of great significance for making better treatment
choices and improving cancer prognosis, but remains a big challenge in clinical practice. In …

Improving precision surgery: A review of current intraoperative nerve tissue fluorescence imaging

LG Wang, SL Gibbs - Current opinion in chemical biology, 2023 - Elsevier
Iatrogenic nerve injury represents one of the most feared surgical complications and
remains a major morbidity across many surgical specialties. Currently, no clinically …

2, 1, 3‐Benzothiadiazole Derivative Small Molecule Fluorophores for NIR‐II Bioimaging

Z Hu, L Feng, P Yang - Advanced Functional Materials, 2024 - Wiley Online Library
Second near‐infrared (NIR‐II) bioimaging technology shows broad application prospects in
the field of biomedical due to its significant superiority in deep tissue penetration and high …

Fluorescent nano-and microparticles for sensing cellular microenvironment: past, present and future applications

G Grasso, F Colella, S Forciniti, V Onesto, H Iuele… - Nanoscale …, 2023 - pubs.rsc.org
The tumor microenvironment (TME) demonstrates distinct hallmarks, including acidosis,
hypoxia, reactive oxygen species (ROS) generation, and altered ion fluxes, which are crucial …

Activity-Based Fluorescence Diagnostics for Cancer

K Fujita, Y Urano - Chemical Reviews, 2024 - ACS Publications
Fluorescence imaging is one of the most promising approaches to achieve intraoperative
assessment of the tumor/normal tissue margins during cancer surgery. This is critical to …

Modular Self‐Assembling Dendrimer Nanosystems for Magnetic Resonance and Multimodality Imaging of Tumors

L Ding, Z Lyu, TA Perles‐Barbacaru… - Advanced …, 2024 - Wiley Online Library
Bioimaging is a powerful tool for diagnosing tumors but remains limited in terms of sensitivity
and specificity. Nanotechnology‐based imaging probes able to accommodate abundant …

Identification of pediatric tumors intraoperatively using indocyanine green (ICG)

L Pio, MHWA Wijnen, S Giuliani, S Sarnacki… - Annals of Surgical …, 2023 - Springer
Background Fluorescence-guided surgery (FGS) with indocyanine green (ICG) is
increasingly applied in pediatric surgical oncology. However, FGS has been mostly reported …