Increasing rates of infection by antibiotic resistant bacteria have led to a resurgence of
interest in bacteriophage (phage) therapy. Several phage therapy studies in animals and …

Against a backdrop of global antibiotic resistance and increasing awareness of the
importance of the human microbiota, there has been resurgent interest in the potential use of …

Bacteriophages, or phages, are viruses that infect bacteria. They were discovered around a
century ago and have been used ever since for therapeutic purposes, particularly in former …

There is a current unmet medical need for the treatment of antibiotic-resistant infections, and
in the absence of approved alternatives, some clinicians are turning to empirical ones, such …

Antimicrobial resistance is increasing despite new treatments being employed. With a
decrease in the discovery rate of novel antibiotics, this threatens to take humankind back to …

Bacteriophages (phages) are viruses that infect bacteria. The “predator–prey” interactions
are recognized as a potentially effective way to treat infections. Phages, as well as phage …

Validated methods for phage selection, host range expansion, and lytic activity
determination are indispensable for maximizing phage therapy outcomes. In this review, we …

Species in the genus Pseudomonas thrive in a diverse set of ecological niches and include
crucial pathogens, such as the human pathogen Pseudomonas aeruginosa and the plant …

The history of phage therapy started with its first clinical application in 1919 and continues its
development to this day. Phages continue to lack any market approval in Western medicine …

Horizontal gene transfer (HGT) can create tremendous genetic diversity in organisms,
especially those which reproduce asexually. The three classical mechanisms for HGT in …