Cilia and mucociliary clearance

XM Bustamante-Marin… - Cold Spring Harbor …, 2017 - cshperspectives.cshlp.org
Mucociliary clearance (MCC) is the primary innate defense mechanism of the lung. The
functional components are the protective mucous layer, the airway surface liquid layer, and …

Mucociliary clearance: pathophysiological aspects

M Munkholm, J Mortensen - Clinical physiology and functional …, 2014 - Wiley Online Library
Mucociliary clearance has long been known to be a significant innate defence mechanism
against inhaled microbes and irritants. Important knowledge has been gathered regarding …

Randomized, Placebo-controlled Clinical Trial of an Aerosolized β2-Agonist for Treatment of Acute Lung Injury

National Heart, Lung, and Blood Institute … - American journal of …, 2011 - atsjournals.org
Rationale: β2-Adrenergic receptor agonists accelerate resolution of pulmonary edema in
experimental and clinical studies. Objectives: This clinical trial was designed to test the …

Environmental pollutants damage airway epithelial cell cilia: Implications for the prevention of obstructive lung diseases

Y Cao, M Chen, D Dong, S Xie, M Liu - Thoracic Cancer, 2020 - Wiley Online Library
Mucociliary epithelium lining the upper and lower respiratory tract constitutes the first line of
defense of the airway and lungs against inhaled pollutants and pathogens. The concerted …

[图书][B] Pharmaceutical inhalation aerosol technology

AJ Hickey - 2003 - taylorfrancis.com
This thoroughly revised and expanded reference provides authoritative discussions on the
physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors …

Tracheobronchomalacia and excessive dynamic airway collapse: current concepts and future directions

A Aslam, J De Luis Cardenas, RJ Morrison… - Radiographics, 2022 - pubs.rsna.org
Tracheobronchomalacia (TBM) and excessive dynamic airway collapse (EDAC) are airway
abnormalities that share a common feature of expiratory narrowing but are distinct …

Addition of long‐acting beta2‐agonists to inhaled steroids versus higher dose inhaled steroids in adults and children with persistent asthma

FM Ducharme, MN Chroinin… - Cochrane Database …, 2010 - cochranelibrary.com
Background In asthmatic patients inadequately controlled on inhaled corticosteroids and/or
those with moderate persistent asthma, two main options are recommended: the …

Mucociliary respiratory epithelium integrity in molecular defense and susceptibility to pulmonary viral infections

Adivitiya, MS Kaushik, S Chakraborty, S Veleri… - Biology, 2021 - mdpi.com
Simple Summary Mucociliary clearance constitutes an innate lung defense mechanism that
is primarily driven by ciliated cells. Respiratory mucus traps pathogens entering the airways …

Addition of long‐acting beta2‐agonists to inhaled steroids as first line therapy for persistent asthma in steroid‐naive adults and children

MN Chroinin, I Greenstone… - Cochrane Database …, 2009 - cochranelibrary.com
Background Consensus statements recommend the addition of long‐acting inhaled ß2‐
agonists (LABA) only in asthmatic patients who are inadequately controlled on inhaled …

Role of air changes per hour (ACH) in possible transmission of airborne infections

F Memarzadeh, W Xu - Building simulation, 2012 - Springer
The cost of nosocomial infections in the United States is estimated to be 4billionto 5 billion
annually. Applying a scientifically based analysis to disease transmission and performing a …