Exosomes and other extracellular vesicles in host–pathogen interactions
An effective immune response requires the engagement of host receptors by pathogen‐
derived molecules and the stimulation of an appropriate cellular response. Therefore, a …
derived molecules and the stimulation of an appropriate cellular response. Therefore, a …
Extracellular vesicles and infectious diseases: new complexity to an old story
JS Schorey, CV Harding - The Journal of clinical …, 2016 - Am Soc Clin Investig
Exosomes and other extracellular microvesicles (ExMVs) have important functions in
intercellular communication and regulation. During the course of infection, these vesicles …
intercellular communication and regulation. During the course of infection, these vesicles …
[HTML][HTML] Role of extracellular vesicles in viral and bacterial infections: pathogenesis, diagnostics, and therapeutics
Extracellular vesicles (EVs), or exosomes, are nanovesicles of endocytic origin that carry
host and pathogen-derived protein, nucleic acid, and lipid cargos. They are secreted by …
host and pathogen-derived protein, nucleic acid, and lipid cargos. They are secreted by …
Epstein–Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating PTEN-dependent pathways in nasopharyngeal carcinoma
L Cai, Y Ye, Q Jiang, Y Chen, X Lyu, J Li… - Nature …, 2015 - nature.com
Abstract Epstein–Barr virus (EBV), aetiologically linked to nasopharyngeal carcinoma
(NPC), is the first human virus found to encode many miRNAs. However, how these viral …
(NPC), is the first human virus found to encode many miRNAs. However, how these viral …
N (6)‐methyladenosine‐binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay
TL Xia, X Li, X Wang, YJ Zhu, H Zhang, W Cheng… - EMBO …, 2021 - embopress.org
Abstract N 6‐methyladenosine (m6A) modification of mRNA mediates diverse cellular and
viral functions. Infection with Epstein–Barr virus (EBV) is causally associated with …
viral functions. Infection with Epstein–Barr virus (EBV) is causally associated with …
EBV-miR-BART7-3p promotes the EMT and metastasis of nasopharyngeal carcinoma cells by suppressing the tumor suppressor PTEN
LM Cai, XM Lyu, WR Luo, XF Cui, YF Ye, CC Yuan… - Oncogene, 2015 - nature.com
The epithelial-mesenchymal transition (EMT) is crucial to cancer progression and
metastasis. Although multiple cellular miRNAs have been identified to regulate the EMT and …
metastasis. Although multiple cellular miRNAs have been identified to regulate the EMT and …
Comprehensive transcriptome and mutational profiling of endemic Burkitt lymphoma reveals EBV type–specific differences
Endemic Burkitt lymphoma (eBL) is the most common pediatric cancer in malaria-endemic
equatorial Africa and nearly always contains Epstein–Barr virus (EBV), unlike sporadic …
equatorial Africa and nearly always contains Epstein–Barr virus (EBV), unlike sporadic …
EBV-miR-BART1-5P activates AMPK/mTOR/HIF1 pathway via a PTEN independent manner to promote glycolysis and angiogenesis in nasopharyngeal carcinoma
X Lyu, J Wang, X Guo, G Wu, Y Jiao, OD Faleti… - PLoS …, 2018 - journals.plos.org
Abnormal metabolism and uncontrolled angiogenesis are two important characteristics of
malignant tumors. The occurrence of both events involves many key molecular changes …
malignant tumors. The occurrence of both events involves many key molecular changes …
EBV-miR-BART8-3p induces epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma cells through activating NF-κB and Erk1/2 …
C Lin, J Zong, W Lin, M Wang, Y Xu, R Zhou… - Journal of Experimental …, 2018 - Springer
Abstract Background Epstein-Barr virus (EBV) is ubiquitously associated with
nasopharyngeal carcinoma (NPC). EBV encodes two groups of microRNAs (miRNAs) which …
nasopharyngeal carcinoma (NPC). EBV encodes two groups of microRNAs (miRNAs) which …
Interplay of viral infection, host cell factors and tumor microenvironment in the pathogenesis of nasopharyngeal carcinoma
SCM Huang, SW Tsao, CM Tsang - Cancers, 2018 - mdpi.com
Undifferentiated nasopharyngeal carcinoma (NPC) is strongly associated with Epstein-Barr
virus (EBV) infection. In addition, heavy infiltration of leukocytes is a common characteristic …
virus (EBV) infection. In addition, heavy infiltration of leukocytes is a common characteristic …