Molecular changes induced by oxidative stress that impair human sperm motility
K Nowicka-Bauer, B Nixon - Antioxidants, 2020 - mdpi.com
A state of oxidative stress (OS) and the presence of reactive oxygen species (ROS) in the
male reproductive tract are strongly correlated with infertility. While physiological levels of …
male reproductive tract are strongly correlated with infertility. While physiological levels of …
Molecular insights into transgenerational non-genetic inheritance of acquired behaviours
Behavioural traits in mammals are influenced by environmental factors, which can interact
with the genome and modulate its activity by complex molecular interplay. Environmental …
with the genome and modulate its activity by complex molecular interplay. Environmental …
Characterisation of mouse epididymosomes reveals a complex profile of microRNAs and a potential mechanism for modification of the sperm epigenome
JN Reilly, EA McLaughlin, SJ Stanger, AL Anderson… - Scientific reports, 2016 - nature.com
Recent evidence has shown that the sperm epigenome is vulnerable to dynamic
modifications arising from a variety of paternal environment exposures and that this legacy …
modifications arising from a variety of paternal environment exposures and that this legacy …
Crosstalk between Sertoli and germ cells in male fertility
S Wu, M Yan, R Ge, CY Cheng - Trends in molecular medicine, 2020 - cell.com
Spermatogenesis is supported by intricate crosstalk between Sertoli cells and germ cells
including spermatogonia, spermatocytes, haploid spermatids, and spermatozoa, which …
including spermatogonia, spermatocytes, haploid spermatids, and spermatozoa, which …
Single-cell RNA sequencing reveals the fragility of male spermatogenic cells to Zika virus-induced complement activation
W Yang, LB Liu, FL Liu, YH Wu, ZD Zhen… - Nature …, 2023 - nature.com
Zika virus (ZIKV) is a potential threat to male reproductive health but the mechanisms
underlying its influence on testes during ZIKV infection remain obscure. To address this …
underlying its influence on testes during ZIKV infection remain obscure. To address this …
Proteomic profiling of mouse epididymosomes reveals their contributions to post-testicular sperm maturation
The functional maturation of spermatozoa that is necessary to achieve fertilization occurs as
these cells transit through the epididymis, a highly specialized region of the male …
these cells transit through the epididymis, a highly specialized region of the male …
Regulation of spermatogenesis: an evolutionary biologist's perspective
S Schlatt, J Ehmcke - Seminars in cell & developmental biology, 2014 - Elsevier
This review describes the regulation of spermatogenesis taking into consideration the
hypothalamic–pituitary gonadal axis, the male reproductive organs and the endocrine and …
hypothalamic–pituitary gonadal axis, the male reproductive organs and the endocrine and …
Oral, short-term exposure to titanium dioxide nanoparticles in Sprague-Dawley rat: focus on reproductive and endocrine systems and spleen
The study explored possible reproductive and endocrine effects of short-term (5 days) oral
exposure to anatase TiO2 nanoparticles (0, 1, 2 mg/kg body weight per day) in rat …
exposure to anatase TiO2 nanoparticles (0, 1, 2 mg/kg body weight per day) in rat …
Microtubules and spermatogenesis
L O'Donnell, MK O'Bryan - Seminars in cell & developmental biology, 2014 - Elsevier
Microtubules are dynamic polymers of tubulin subunits that underpin many essential cellular
processes, such as cell division and migration. Spermatogenesis is the process by which …
processes, such as cell division and migration. Spermatogenesis is the process by which …
Spata6 is required for normal assembly of the sperm connecting piece and tight head–tail conjunction
“Pinhead sperm,” or “acephalic sperm,” a type of human teratozoospermia, refers to the
condition in which ejaculate contains mostly sperm flagella without heads. Family clustering …
condition in which ejaculate contains mostly sperm flagella without heads. Family clustering …