Childhood asthma

L Lowe, A Custovic, A Woodcock - Current allergy and asthma reports, 2004 - Springer
The prevalence of asthma and wheezing illness in children has increased substantially over
recent decades and places a large burden on health care resources. Despite increasing …

Predicting adult asthma in childhood

JM Vonk, HM Boezen - Current opinion in pulmonary medicine, 2006 - journals.lww.com
Predicting adult asthma in childhood : Current Opinion in Pulmonary Medicine Predicting adult
asthma in childhood : Current Opinion in Pulmonary Medicine Log in or Register Subscribe to …

[HTML][HTML] Nicotine stimulates nerve growth factor in lung fibroblasts through an NFκB-dependent mechanism

C Wongtrakool, K Grooms, KM Bijli, K Crothers… - Plos one, 2014 - journals.plos.org
Rationale Airway hyperresponsiveness (AHR) is classically found in asthma, and persistent
AHR is associated with poor asthma control. Although airway smooth muscle (ASM) cells …

Activation of endogenous GABAA channels on airway smooth muscle potentiates isoproterenol-mediated relaxation

G Gallos, NR Gleason, Y Zhang… - … of Physiology-Lung …, 2008 - journals.physiology.org
Reactive airway disease predisposes patients to episodes of acute smooth muscle mediated
bronchoconstriction. We have for the first time recently demonstrated the expression and …

Effects of Inhaled Corticosteroids, Leukotriene Receptor Antagonists, or Both, Plus Long-Acting β2-Agonists on Asthma Pathophysiology: a Review of the Evidence

AM Vignola - Drugs, 2003 - Springer
Chronic inflammation and smooth muscle dysfunction are consistent features of asthma, and
are responsible for disease progression and airway remodelling. The development of …

Association of symptom control with changes in lung function, bronchial hyperresponsiveness, and exhaled nitric oxide after inhaled corticosteroid treatment in …

GM Park, HW Han, JY Kim, E Lee, HJ Cho… - Allergology …, 2016 - jstage.jst.go.jp
Background: A key therapeutic approach to asthma, which is characterized by chronic
airway inflam-mation, is inhaled corticosteroid (ICS). This study evaluated the association of …

The role of lung inflation in airway hyperresponsiveness and in asthma

N Scichilone, A Togias - Current allergy and asthma reports, 2004 - Springer
Airway hyperresponsiveness (AHR) is a fundamental phenomenon in asthma that can
explain many aspects of the clinical manifestations of the disease. Several theories on the …

[HTML][HTML] Salmeterol and cytokines modulate inositol-phosphate signalling in Human airway smooth muscle cells via regulation at the receptor locus

N Smith, CA Browning, N Duroudier, C Stewart… - Respiratory …, 2007 - Springer
Background Airway hyper-responsiveness (AHR) is a key feature of asthma and a causal
relationship between airway inflammation and AHR has been identified. The aim of the …

The effect of beclomethasone dipropionate in ultrafine particles on bronchial hyper‐reactivity in young children

CL Costa‐Katz, G Livnat, F Hakim, D Vilozni… - Acta …, 2012 - Wiley Online Library
Aim: Bronchial hyper‐reactivity (BHR) provides a tool for asthma diagnosis, assessment of
severity and response to treatment. The effect of beclomethasone dipropionate in ultrafine …

[HTML][HTML] Airway hyperresponsiveness and quality of life in Western red cedar asthmatics removed from exposure

JQ He, M Chan-Yeung, C Carlsten - Plos one, 2012 - journals.plos.org
Objectives Most western red cedar asthmatics (WRCA) continue to have symptoms even
after removal from exposure. Consequently, health-related quality of life (HRQL) is often …