Immune memory is a defining feature of the acquired immune system, but activation of the
innate immune system can also result in enhanced responsiveness to subsequent triggers …

The last few years have witnessed an increasing body of evidence that challenges the
traditional view that immunological memory is an exclusive trait of the adaptive immune …

Increasing evidence supports a central role of the immune system in sepsis, but the current
view of how sepsis affects immunity, and vice versa, is still rudimentary. The European …

Intergenerational inheritance of immune traits linked to epigenetic modifications has been
demonstrated in plants and invertebrates. Here we provide evidence for transmission of …

In addition to the roles of endothelial cells (ECs) in physiological processes, ECs actively
participate in both innate and adaptive immune responses. We previously reported that, in …

Trained immunity enhances the responsiveness of immune cells to subsequent infections or
vaccinations. Here we demonstrate that pre-vaccination with bacteria-derived outer …

Sepsis involves simultaneous hyperactivation of the immune system and immune paralysis,
leading to both organ dysfunction and increased susceptibility to secondary infections. Acute …

Trained immunity is a process in which innate immune cells undergo functional
reprogramming in response to pathogens or damage‐associated molecules leading to an …

Dendritic cells (DCs), a vital component of the innate immune system, are considered to lack
antigen specificity and be devoid of immunological memory. Strategies that can induce …

Neuroimmunological diseases and their treatment compromise the immune system, thereby
increasing the risk of infections and serious illness. Consequently, vaccinations to protect …