Carbohydrates are essential mediators of many processes in health and disease. They
regulate self-/non-self-discrimination, are key elements of cellular communication, cancer …

Antimicrobial resistance is an increasing phenomenon that is threatening global health.
Tuberculosis causative bacteria and several resistant and multidrug-resistant bacteria are …

Emerging resistance to all available antibiotics highlights the need to develop new
antibiotics with novel mechanisms of action. Most of the currently used antibiotics target …

Chronic rhinosinusitis (CRS) is a debilitating condition characterized by long-lasting
inflammation of the paranasal sinuses. It affects a significant portion of the population …

Many approaches are being pursued to address the major global health challenge posed by
the increasing resistance of pathogenic bacteria to antibacterial agents. One of the …

Recently, non-covalent reactions have emerged as approaches to improve the
physicochemical properties of active pharmaceutical ingredients (API), including antibiotics …

In this work, β-thiogalactoside mimetics bearing 1, 1-diarylmethylene or benzophenone
aglycons have been prepared and assayed for their affinity towards LecA, a lectin and …

Antimicrobial resistance (AMR) is an increasingly concerning phenomenon that requires
urgent attention because it poses a threat to human and animal health. Bacteria undergo …

Pseudomonas aeruginosa contributes to frequent, persistent, and, often, polymicrobial
respiratory tract infections for individuals with cystic fibrosis (CF). Chronic CF infections lead …

Infections with multidrug‐resistant Gram‐negative bacteria constitute a silent pandemic
threat that is increasing globally. A major technical and scientific hurdle hampering the …