[HTML][HTML] A journey to the central nervous system: routes of flaviviral neuroinvasion in human disease

EM Marshall, MPG Koopmans, B Rockx - Viruses, 2022 - mdpi.com
Many arboviruses, including viruses of the Flavivirus genus, are known to cause severe
neurological disease in humans, often with long-lasting, debilitating sequalae in surviving …

[HTML][HTML] Modeling virus-induced inflammation in zebrafish: A balance between infection control and excessive inflammation

C Sullivan, BL Soos, PJ Millard, CH Kim… - Frontiers in …, 2021 - frontiersin.org
The inflammatory response to viral infection in humans is a dynamic process with complex
cell interactions that are governed by the immune system and influenced by both host and …

[HTML][HTML] Concomitant pyroptotic and apoptotic cell death triggered in macrophages infected by Zika virus

C Wen, Y Yu, C Gao, X Qi, CJ Cardona, Z Xing - PLos One, 2022 - journals.plos.org
Zika virus (ZIKV) is a positive-sense RNA flavivirus and can cause serious neurological
disorders including microcephaly in infected fetuses. As a mosquito-borne arbovirus, it …

Host-microbe interactions at the blood-brain barrier through the lens of induced pluripotent stem cell-derived brain-like endothelial cells

N Vollmuth, J Sin, BJ Kim - Mbio, 2024 - Am Soc Microbiol
Microbe-induced meningoencephalitis/meningitis is a life-threatening infection of the central
nervous system (CNS) that occurs when pathogens are able to cross the blood-brain barrier …

Tembusu Virus entering the central nervous system caused nonsuppurative encephalitis without disrupting the blood-brain barrier

S Yang, Y Huang, Y Shi, X Bai, P Yang… - Journal of …, 2021 - Am Soc Microbiol
Tembusu virus (TMUV) is an emerging and reemerging zoonotic pathogen that has
adversely affected the poultry industry in recent years. TMUV disease is characterized by …

[HTML][HTML] Advancement in the development of therapeutics against Zika virus infection

K Li, Q Ji, S Jiang, N Zhang - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Zika virus (ZIKV), a re-emerging arbovirus, causes teratogenic effects on the fetus and
normal nerve functions, resulting in harmful autoimmune responses, which call for the …

[HTML][HTML] Protruding cantilever microelectrode array to monitor the inner electrical activity of cerebral organoids

O Phouphetlinthong, E Partiot, C Bernou, A Sebban… - Lab on a Chip, 2023 - pubs.rsc.org
Stem cell-derived cerebral organoids are artificially grown miniature organ-like structures
mimicking embryonic brain architecture. They are composed of multiple neural cell types …

Shared molecular signatures across zika virus infection and multiple sclerosis highlight AP-1 transcription factor as a potential player in post-ZIKV MS-like phenotypes

EV da Silva, FL Fontes-Dantas, TV Dantas… - Molecular …, 2023 - Springer
Zika virus (ZIKV) is an arbovirus of the Flaviviridae genus that has rapidly disseminated from
across the Pacific to the Americas. Robust evidence has indicated a crucial role of ZIKV in …

[HTML][HTML] Zika virus-infected monocyte exosomes mediate cell-to-cell viral transmission

PP Martínez-Rojas, V Monroy-Martínez… - Cells, 2024 - mdpi.com
Zika fever is a reemerging arthropod-borne viral disease; however, Zika virus (ZIKV) can be
transmitted by other, non-vector means. Severe Zika fever is characterized by neurological …

Zika virus replication in myeloid cells during acute infection is vital to viral dissemination and pathogenesis in a mouse model

EM McDonald, J Anderson, J Wilusz, GD Ebel… - Journal of …, 2020 - Am Soc Microbiol
Zika virus (ZIKV) can establish infection in immune privileged sites such as the testes, eye,
and placenta. Whether ZIKV infection of white blood cells is required for dissemination of the …