Introduction Tumors pose a significant global economic and health burden, with
conventional cancer treatments lacking tumor specificity, leading to limited efficiency and …

Multiple sclerosis (MS), a debilitating autoimmune inflammatory disease that affects the
brain and spinal cord, causes demyelination of neurons, axonal damage, and …

Background: PD-1 immune checkpoint inhibitors are not effective in treating all patients with
hepatocellular carcinoma (HCC) and regulatory T cells (Tregs) may determine the …

In situ vaccination is a desirable strategy for cancer immunotherapy due to its convenience
and capacity to target tumor antigens. Here, an in situ nanovaccine based on a cationic …

Regulatory T cells (Treg) impede effective antitumor immunity. However, the role of Tregs in
the clinical outcomes of patients with triple-negative breast cancer (TNBC) remains …

Gastric cancer (GC) remains one of the most common malignancies worldwide. Despite
immune-checkpoint inhibitors (ICIs) has revolutionized cancer treatment and obtained …

Glioblastoma (GBM) is the most malignant of astrocytomas mainly involving the cerebral
hemispheres and the cerebral cortex. It is one of the fatal and refractory solid tumors, with a …

Background The 5-year survival rate of multiple myeloma (MM) in China is less than 40%,
with considerable individual heterogeneity. Gene mutations are important predictive …

Purpose of review Antibody-mediated rejection (AbMR) after solid organ transplantation is
tightly controlled by multiple cells of the immune system. Tfh and Tfr cells are essential …

Gastric cancer (GC) is a highly aggressive malignancy that remains a significant contributor
to cancer-related mortality worldwide, despite a decline in incidence in recent years. Early …