Idiopathic pulmonary fibrosis: pathogenesis and management

G Sgalla, B Iovene, M Calvello, M Ori, F Varone… - Respiratory …, 2018 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease
characterized by the aberrant accumulation of fibrotic tissue in the lungs parenchyma …

Idiopathic pulmonary fibrosis (IPF): an overview

SL Barratt, A Creamer, C Hayton… - Journal of clinical …, 2018 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterised by chronic,
progressive scarring of the lungs and the pathological hallmark of usual interstitial …

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study

RJ Allen, J Porte, R Braybrooke, C Flores… - The Lancet respiratory …, 2017 - thelancet.com
Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with
high mortality, uncertain cause, and few treatment options. Studies have identified a …

Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study

RG Jenkins, JK Simpson, G Saini… - The lancet Respiratory …, 2015 - thelancet.com
Background Idiopathic pulmonary fibrosis, a progressive and inevitably fatal disorder, has a
highly variable clinical course. Biomarkers that reflect disease activity are urgently needed to …

Molecular mechanisms and cellular contribution from lung fibrosis to lung cancer development

AV Samarelli, V Masciale, B Aramini, GP Coló… - International journal of …, 2021 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial lung
disease (ILD) of unknown aetiology, with a median survival of 2–4 years from the time of …

Interstitial lung disease

KM Antoniou, GA Margaritopoulos… - European …, 2014 - Eur Respiratory Soc
Interstitial lung diseases are a group of diffuse parenchymal lung disorders associated with
substantial morbidity and mortality. Knowledge achieved in recent years has resulted in the …

Idiopathic pulmonary fibrosis: diagnosis, epidemiology and natural history

G Sgalla, A Biffi, L Richeldi - Respirology, 2016 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrosing lung disorder of
unknown aetiology whose diagnosis involves the careful exclusion of secondary causes for …

[HTML][HTML] Diagnostic and prognostic biomarkers for chronic fibrosing interstitial lung diseases with a progressive phenotype

Y Inoue, RJ Kaner, J Guiot, TM Maher, S Tomassetti… - Chest, 2020 - Elsevier
Biomarkers have the potential to become central to the clinical evaluation and monitoring of
patients with chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype …

Blood biomarkers in idiopathic pulmonary fibrosis

J Guiot, C Moermans, M Henket, JL Corhay, R Louis - Lung, 2017 - Springer
Purpose Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disease of
unknown origin whose incidence has been increasing over the latest decade partly as a …

Biomarkers of collagen synthesis predict progression in the PROFILE idiopathic pulmonary fibrosis cohort

LA Organ, AMR Duggan, E Oballa, SC Taggart… - Respiratory …, 2019 - Springer
Idiopathic pulmonary fibrosis (IPF) is characterised by excessive extracellular matrix (ECM)
deposition and remodelling. Measuring this activity provides an opportunity to develop tools …