AMPA receptor and metabotropic glutamate receptor 1 adaptations in the nucleus accumbens core during incubation of methamphetamine craving

CH Murray, JA Loweth, M Milovanovic… - …, 2019 - nature.com
Cue-induced drug craving progressively intensifies after withdrawal from self-administration
of cocaine, methamphetamine, and other drugs of abuse, a phenomenon termed incubation …

Effect of novel allosteric modulators of metabotropic glutamate receptors on drug self-administration and relapse: a review of preclinical studies and their clinical …

D Caprioli, Z Justinova, M Venniro, Y Shaham - Biological psychiatry, 2018 - Elsevier
Results from preclinical rodent studies during the last 20 years implicated glutamate
neurotransmission in different brain regions in drug self-administration and rodent models of …

Role of nucleus accumbens core but not shell in incubation of methamphetamine craving after voluntary abstinence

LM Rossi, I Reverte, D Ragozzino, A Badiani… - …, 2020 - nature.com
We recently introduced an animal model to study incubation of drug craving after prolonged
voluntary abstinence, mimicking the human condition of relapse after successful …

[HTML][HTML] Voluntary alcohol intake alters the motivation to seek intravenous oxycodone and neuronal activation during the reinstatement of oxycodone and sucrose …

CS Wilkinson, HL Blount, S Davis, G Rojas, L Wu… - Scientific Reports, 2023 - nature.com
Opioid-alcohol polysubstance use is prevalent and worsens treatment outcomes. Here we
assessed whether co-consumption of oxycodone and alcohol influence the intake of one …

A novel cholinergic projection from the lateral parabrachial nucleus and its role in methamphetamine-primed conditioned place preference

T He, W Chen, Y Fan, X Xu, H Guo, N Li… - Brain …, 2022 - academic.oup.com
Drug relapse is a big clinical challenge in the treatment of addiction, but its neural circuit
mechanism is far from being fully understood. Here, we identified a novel cholinergic …

[HTML][HTML] Compulsive methamphetamine taking and abstinence in the presence of adverse consequences: Epigenetic and transcriptional consequences in the rat brain

JL Cadet, R Patel, S Jayanthi - Pharmacology Biochemistry and Behavior, 2019 - Elsevier
Methamphetamine addiction is characterized by compulsive binges of drug intake despite
adverse life consequences. A model of methamphetamine self-administration that includes …

[HTML][HTML] Inactivation of the prelimbic cortex impairs the context-induced reinstatement of ethanol seeking

P Palombo, RM Leao, PC Bianchi… - Frontiers in …, 2017 - frontiersin.org
Evidence indicates that drug relapse in humans is often provoked by exposure to the self-
administered drug-associated context. An animal model called “ABA renewal procedure” …

Profiling circular RNA in methamphetamine-treated primary cortical neurons identified novel circRNAs related to methamphetamine addiction

J Li, Q Shi, Q Wang, X Tan, K Pang, X Liu, S Zhu… - Neuroscience …, 2019 - Elsevier
Methamphetamine (METH) has been a worldwide health threat for years. Recent studies
have reported that circular RNA (circRNA) are highly abundant and dynamically expressed …

Role of dorsal striatum histone deacetylase 5 in incubation of methamphetamine craving

X Li, MB Carreria, KR Witonsky, T Zeric, OM Lofaro… - Biological …, 2018 - Elsevier
Background Methamphetamine (meth) seeking progressively increases after withdrawal
(incubation of meth craving). We previously demonstrated an association between histone …

[HTML][HTML] Linking drug and food addiction: an overview of the shared neural circuits and behavioral phenotype

A Passeri, D Municchi, G Cavalieri… - Frontiers in Behavioral …, 2023 - frontiersin.org
Despite a lack of agreement on its definition and inclusion as a specific diagnosable
disturbance, the food addiction construct is supported by several neurobiological and …