Role of orbitofrontal cortex in incubation of oxycodone craving in male rats
RD Altshuler, ES Yang, KT Garcia, IR Davis… - Addiction …, 2021 - Wiley Online Library
One of the main challenges in treating opioid‐use disorders is relapse during abstinence,
triggered by re‐exposure to drug‐associated cues. Previous studies have demonstrated that …
triggered by re‐exposure to drug‐associated cues. Previous studies have demonstrated that …
Central nucleus of the amygdala as a common substrate of the incubation of drug and natural reinforcer seeking
D Roura‐Martínez, M Ucha, J Orihuel… - Addiction …, 2020 - Wiley Online Library
Relapse into drug use is a major problem faced by recovering addicts. In humans, an
intensification of the desire for the drug induced by environmental cues—incubation of drug …
intensification of the desire for the drug induced by environmental cues—incubation of drug …
Role of piriform cortex and its afferent projections in relapse to fentanyl seeking after food choice-induced voluntary abstinence
SM Claypool, DJ Reiner, S Behdin… - Journal of …, 2023 - Soc Neuroscience
We previously demonstrated a role of piriform cortex (Pir) in relapse to fentanyl seeking after
food choice-induced voluntary abstinence. Here, we used this model to further study the role …
food choice-induced voluntary abstinence. Here, we used this model to further study the role …
Role of anterior intralaminar nuclei of thalamus projections to dorsomedial striatum in incubation of methamphetamine craving
X Li, KR Witonsky, OM Lofaro, F Surjono… - Journal of …, 2018 - Soc Neuroscience
Relapse to methamphetamine (Meth) seeking progressively increases after withdrawal from
drug self-administration (incubation of Meth craving). We previously demonstrated a role of …
drug self-administration (incubation of Meth craving). We previously demonstrated a role of …
Optogenetic activation of the central amygdala generates addiction‐like preference for reward
RL Tom, A Ahuja, H Maniates… - European Journal of …, 2019 - Wiley Online Library
Drug and behavioural addictions are characterized by an intense and focused pursuit of a
single reward above all others. Pursuit of the addictive reward is often compulsively sought …
single reward above all others. Pursuit of the addictive reward is often compulsively sought …
Incubation of extinction responding and cue‐induced reinstatement, but not context‐or drug priming‐induced reinstatement, after withdrawal from methamphetamine
S Adhikary, D Caprioli, M Venniro… - Addiction …, 2017 - Wiley Online Library
In rats trained to self‐administer methamphetamine, extinction responding in the presence of
drug‐associated contextual and discrete cues progressively increases after withdrawal …
drug‐associated contextual and discrete cues progressively increases after withdrawal …
GABA-induced inactivation of dorsal midline thalamic subregions has distinct effects on emotional behaviors
JR Barson, SF Leibowitz - Neuroscience letters, 2015 - Elsevier
The paraventricular nucleus of the thalamus (PVT) is a key node integrating information
about emotion and relaying output to other limbic structures influencing motor behavior. With …
about emotion and relaying output to other limbic structures influencing motor behavior. With …
Comparative analysis of the modulation of perineuronal nets in the prefrontal cortex of rats during protracted withdrawal from cocaine, heroin and sucrose self …
D Roura-Martínez, P Díaz-Bejarano, M Ucha… - …, 2020 - Elsevier
Relapse into drug use is a significant problem for people recovering from addiction. The
ability that conditioned cues have to reinstate and reinvigorate drug-seeking is potentiated …
ability that conditioned cues have to reinstate and reinvigorate drug-seeking is potentiated …
Self-administration of entactogen psychostimulants dysregulates gamma-aminobutyric acid (GABA) and kappa opioid receptor signaling in the central nucleus of the …
Male rats escalate intravenous self-administration of entactogen psychostimulants, 3, 4-
methylenedioxymethcathinone (methylone) and 3, 4-methylenedioxymethamphetamine …
methylenedioxymethcathinone (methylone) and 3, 4-methylenedioxymethamphetamine …
Genome-wide transcriptional profiling of central amygdala and orbitofrontal cortex during incubation of methamphetamine craving
Methamphetamine (Meth) seeking progressively increases after withdrawal (incubation of
Meth craving), but the transcriptional mechanisms that contribute to this incubation are …
Meth craving), but the transcriptional mechanisms that contribute to this incubation are …