Biomarkers in cardiovascular clinical trials: past, present, future

SA Halim, LK Newby, EM Ohman - Clinical Chemistry, 2012 - academic.oup.com
BACKGROUND Cardiovascular (CV) clinical trials are instrumental in understanding
treatment effects and offer insights into the natural progression of CV disease. Biomarkers …

[HTML][HTML] Use of high-dose erythropoietin for repair after injury: A comparison of outcomes in heart and kidney

GC Gobe, C Morais, DA Vesey… - Journal of …, 2013 - ncbi.nlm.nih.gov
Context: There is a need to define the exact benefits and contraindications of use of high-
dose recombinant human erythropoietin (EPO) for its non-hematopoietic function as a …

RNY-derived small RNAs as a signature of coronary artery disease

E Repetto, L Lichtenstein, Z Hizir, N Tekaya… - BMC medicine, 2015 - Springer
Background Data from next generation sequencing technologies uncovered the existence of
many classes of small RNAs. Recent studies reported that small RNAs are released by cells …

The cellular biology of atherosclerosis with atherosclerotic lesion classification and biomarkers

L Melaku, A Dabi - Bulletin of the National Research Centre, 2021 - Springer
Background Atherosclerosis is a chronic lipid-driven inflammatory disease with infiltration of
low-density lipoprotein and is considered as the pivotal step in plaque formation. The aim of …

Serum salusin-α levels are inversely correlated with the presence and severity of coronary artery disease

SL Du, WJ Wang, J Wan, YG Wang… - … Journal of Clinical …, 2013 - Taylor & Francis
We sought to measure serum salusin-α levels in patients with coronary artery disease (CAD)
and to assess their correlation with the severity of the disease. We enrolled 172 patients with …

Biomarkers for diagnosis of the vulnerable atherosclerotic plaque

TG Giannakopoulos, ED Avgerinos… - Interventional …, 2011 - search.proquest.com
Atherosclerosis is a systemic disease affecting all vascular beds. The atherosclerotic plaque,
as a first manifestation of the disease, involves a complex pathophysiological mechanism …

Association of the L3MBTL3 rs1125970 and rs4897367 gene polymorphisms with coronary heart disease susceptibility in the Chinese population: a case-control …

Y Li, J Zhang, J He, X Chen, X Zhang… - Journal of …, 2022 - journals.lww.com
Coronary heart disease (CHD) is a prevalent heart disease with the high incidence and
mortality rates worldwide, and its pathogenesis is related to genetic factors. L3MBTL3 has …

[PDF][PDF] Serum interleukin-6 and interferon-gamma are associated with the severity of coronary disease in patients with acute coronary syndrome and type-2 diabetes

L Hao, YS Liu, N Liu, X Wang, AQ Qin, WD Jiang… - Int J Clin Exp …, 2016 - e-century.us
A number of studies have suggested that interleukin 6 (IL-6) and interferon-gamma (IFN-γ)
have pathophysiologic roles in cardiovascular diseases. In view of recent evidence that …

Elevated soluble CD40 ligand in diabetic patients with painless myocardial infarction

Y Huang, J Qiu, D Zhang, G Qiu - Biofactors, 2011 - Wiley Online Library
Because a useful biomarker for painless myocardial infarction (MI) has yet to be identified,
the aim of this study was to identify a biomarker for diabetic patients with painless MI. A case …

Valeur diagnostique des petits ARN dérivés des ARNY (ou RNY) dans les cardiopathies coronariennes

Z Hizir, M Trabucchi, E Repetto - médecine/sciences, 2016 - medecinesciences.org
Régulation de l'expression de petits ARN dérivés des RNY dans les lésions
athérosclérotiques. Les LDL de la circulation sanguine s' accumulent dans la paroi …