Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-
tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells …

The outcome of an encounter between a cytotoxic cell and a potential target cell depends on
the balance of signals from inhibitory and activating receptors. Natural Killer group 2D …

Non-specific cytotoxic cells (NCC) are important cytotoxic leukocytes in teleost immune
system. However, the NCC subsets have not been clarified. Thus, we create a …

Background Patients face a serious threat if a solid tumor leaves behind partial residuals or
cannot be completely removed after surgical resection. Immunotherapy has attracted …

Cancer immunotherapies often modulate macrophage effector function by introducing either
targeting antibodies that activate Fcγ receptors (FcγRs) or blocking antibodies that disrupt …

Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of
animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular …

There is much interest in the potential use of Cox-2 selective inhibitors in combination with
other cancer therapeutics. Malignancies of hematopoietic and non-hematopoietic origin …

Bloom syndrome (BSyn) is an autosomal recessive disorder caused by variants in the BLM
gene, which is involved in genome stability. Patients with BSyn present with poor growth …

Influenza virus targets epithelial cells in the upper respiratory tract. Natural Killer (NK) cell-
mediated early innate defense responses to influenza infection include the killing of infected …

Receptors on T and NK cells systematically propagate highly complex signaling cascades
that direct immune effector functions, leading to protective immunity. While extensive studies …