SARS-CoV-2-specific T cells in the changing landscape of the COVID-19 pandemic

A Bertoletti, N Le Bert, AT Tan - Immunity, 2022 - cell.com
Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, multiple severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with increasing ability to …

SARS-CoV-2 Omicron variants: burden of disease, impact on vaccine effectiveness and need for variant-adapted vaccines

S Pather, SA Madhi, BJ Cowling, P Moss… - Frontiers in …, 2023 - frontiersin.org
The highly transmissible Omicron (B. 1.1. 529) variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) was first detected in late 2021. Initial Omicron waves were …

Immunogenicity and reactogenicity of SARS-CoV-2 vaccines BNT162b2 and CoronaVac in healthy adolescents

JS Rosa Duque, X Wang, D Leung, SMS Cheng… - Nature …, 2022 - nature.com
We present an interim analysis of a registered clinical study (NCT04800133) to establish
immunobridging with various antibody and cellular immunity markers and to compare the …

[HTML][HTML] Defending against SARS-CoV-2: The T cell perspective

P Almendro-Vázquez, R Laguna-Goya… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2-specific T cell response has been proven essential for viral clearance, COVID-
19 outcome and long-term memory. Impaired early T cell-driven immunity leads to a severe …

Heterologous vector versus homologous mRNA COVID-19 booster vaccination in non-seroconverted immunosuppressed patients: a randomized controlled trial

D Mrak, D Sieghart, E Simader, S Tobudic… - Nature …, 2022 - nature.com
Impaired response to COVID-19 vaccination is of particular concern in immunosuppressed
patients. To determine the best vaccination strategy for this vulnerable group we performed …

[PDF][PDF] Evolution of long-term vaccine-induced and hybrid immunity in healthcare workers after different COVID-19 vaccine regimens

SC Moore, B Kronsteiner, S Longet, S Adele, AS Deeks… - Med, 2023 - cell.com
Background Both infection and vaccination, alone or in combination, generate antibody and
T cell responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Silent battles: immune responses in asymptomatic SARS-CoV-2 infection

N Le Bert, T Samandari - Cellular & Molecular Immunology, 2024 - nature.com
SARS-CoV-2 infections manifest with a broad spectrum of presentations, ranging from
asymptomatic infections to severe pneumonia and fatal outcomes. This review centers on …

[HTML][HTML] Combined anti-S1 and anti-S2 antibodies from hybrid immunity elicit potent cross-variant ADCC against SARS-CoV-2

MD Grant, K Bentley, CA Fielding, KM Hatfield… - JCI insight, 2023 - ncbi.nlm.nih.gov
Antibodies capable of neutralizing SARS-CoV-2 are well studied, but Fc receptor–
dependent antibody activities that can also significantly impact the course of infection have …

[HTML][HTML] Initial immune response after exposure to Mycobacterium tuberculosis or to SARS-COV-2: similarities and differences

A Aiello, S Najafi-Fard, D Goletti - Frontiers in Immunology, 2023 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) and Coronavirus disease-
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …

T‐cell activation–induced marker assays in health and disease

C Poloni, C Schonhofer, S Ivison… - … and Cell Biology, 2023 - Wiley Online Library
Activation‐induced marker (AIM) assays have proven to be an accessible and rapid means
of antigen‐specific T‐cell detection. The method typically involves short‐term incubation of …