Oral polio vaccine stockpile modeling: insights from recent experience

KM Thompson, DA Kalkowska… - Expert Review of …, 2023 - Taylor & Francis
Background Achieving polio eradication requires ensuring the delivery of sufficient supplies
of the right vaccines to the right places at the right times. Despite large global markets …

[HTML][HTML] Effectiveness of poliovirus vaccines against circulating vaccine-derived type 2 poliomyelitis in Nigeria between 2017 and 2022: a case-control study

LV Cooper, TB Erbeto, AA Danzomo… - The Lancet Infectious …, 2024 - thelancet.com
Summary Background Between 2018 and 2022, Nigeria experienced continuous
transmission of circulating vaccine-derived type 2 poliovirus (cVDPV2), with 526 cases of …

[HTML][HTML] Safety of the novel oral poliovirus vaccine type 2 (nOPV2) in infants and young children aged 1 to< 5 years and lot-to-lot consistency of the immune response …

M Ochoge, AC Futa, A Umesi, L Affleck, L Kotei… - The Lancet, 2024 - thelancet.com
Background Novel oral poliovirus vaccine type 2 (nOPV2) has been engineered to improve
the genetic stability of Sabin oral poliovirus vaccine (OPV) and reduce the emergence of …

[HTML][HTML] Tolerability, safety, and immunogenicity of the novel oral polio vaccine type 2 in children aged 6 weeks to 59 months in an outbreak response campaign in …

AO Bashorun, L Kotei, O Jawla, AF Jallow… - The Lancet Infectious …, 2024 - thelancet.com
Background Novel oral polio vaccine type 2 (nOPV2) has been used to interrupt circulating
vaccine-derived poliovirus type 2 outbreaks following its WHO emergency use listing. This …

[HTML][HTML] Halting vaccine-derived poliovirus circulation: the novel type 2 oral vaccine might not be enough

TG Nyenswah, JL Schue - The Lancet Global Health, 2023 - thelancet.com
Polio eradication remains elusive, and its progress has been hampered by the COVID-19
pandemic. 1 Wild-type polioviruses are endemic in two countries (Afghanistan and …

First Africa-based clinical trial for novel type 2 oral poliovirus vaccine

LV Cooper, IM Blake - The Lancet, 2024 - thelancet.com
The Global Polio Eradication Initiative owes much of its success in vastly reducing wild
poliovirus transmission globally to the use of live-attenuated Sabin oral poliovirus vaccine …

Impact of supplementary immunization activities using novel oral polio vaccine type 2 during a large outbreak of circulating vaccine-derived poliovirus in Nigeria

A Voorman, H Lyons, F Shuaib… - The Journal of …, 2024 - academic.oup.com
Background Novel oral poliovirus vaccine (OPV) type 2 (nOPV2) has been made available
for outbreak response under an emergency use listing authorization based on supportive …

nOPV2 development as a global effort for polio outbreak response

AS Bandyopadhyay, S Zipursky - The Lancet Global Health, 2023 - thelancet.com
We are responding to some misinfor mation and misunder standing promulgated by the
Comment by Tolbert Nyenswah and Jessica Schue (June, 2023) 1 on the Article by Stephen …

Polio vaccines: hope, hype, and history repeating?

R Fortner - bmj, 2023 - bmj.com
Polio vaccines: hope, hype, and history repeating? Page 1 Polio vaccines: hope, hype, and
history repeating? Announcement of new polio vaccines has once again raised hopes of …

[HTML][HTML] nOPV2 development as a global effort for polio outbreak response–Authors' reply

TG Nyenswah, JL Schue - The Lancet Global Health, 2023 - thelancet.com
We would like to express our gratitude to Ananda Bandyopadhyay and Simona Zipursky for
taking the time to read and respond to our Comment1 on the results presented by Stephen …