Systemic immune mechanisms in atopic dermatitis and psoriasis with implications for treatment

E Guttman‐Yassky, JG Krueger… - Experimental …, 2018 - Wiley Online Library
Atopic dermatitis (AD) and psoriasis are inflammatory skin diseases that negatively affect
patients' quality of life. Although distinctions exist between these diseases, both are …

Contrasting pathogenesis of atopic dermatitis and psoriasis—part I: clinical and pathologic concepts

E Guttman-Yassky, KE Nograles, JG Krueger - Journal of Allergy and …, 2011 - Elsevier
Atopic dermatitis and psoriasis are 2 of the most common inflammatory skin diseases. They
are similar in that they are complex inherited diseases involving genes that encode immune …

PSORS2 is due to mutations in CARD14

CT Jordan, L Cao, EDO Roberson, KC Pierson… - The American Journal of …, 2012 - cell.com
Psoriasis is a common, immune-mediated genetic disorder of the skin and is associated with
arthritis in approximately 30% of cases. Previously, we localized PSORS2 (psoriasis …

Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis

CT Jordan, L Cao, EDO Roberson, S Duan… - The American Journal of …, 2012 - cell.com
Psoriasis is a common inflammatory disorder of the skin and other organs. We have
determined that mutations in CARD14, encoding a nuclear factor of kappa light chain …

Th17 and Th22 cells in psoriatic arthritis and psoriasis

H Benham, P Norris, J Goodall, MD Wechalekar… - Arthritis research & …, 2013 - Springer
Introduction The aim of this study was to characterize interleukin 17 (IL-17) and interleukin
22 (IL-22) producing cells in peripheral blood (PB), skin, synovial fluid (SF) and synovial …

Contrasting pathogenesis of atopic dermatitis and psoriasis—part II: immune cell subsets and therapeutic concepts

E Guttman-Yassky, KE Nograles, JG Krueger - Journal of Allergy and …, 2011 - Elsevier
Atopic dermatitis (AD) and psoriasis are among the most common inflammatory skin
diseases. In the first part of this 2-part review, we discussed the similarities and differences …

Psoriasis genetics: breaking the barrier

EDO Roberson, AM Bowcock - Trends in Genetics, 2010 - cell.com
Psoriasis is a common incurable inflammatory skin disease affecting 2–3% of the European
population. Psoriatic skin contains large numbers of immune cells which produce many …

Psoriasis, psoriatic arthritis and increased risk of incident Crohn's disease in US women

WQ Li, JL Han, AT Chan, AA Qureshi - Annals of the rheumatic …, 2013 - ard.bmj.com
Objective Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative
colitis (UC), shares clinical and immunological features with psoriasis. Genome-wide …

Obesity and risk of incident psoriatic arthritis in US women

W Li, J Han, AA Qureshi - Annals of the rheumatic diseases, 2012 - ard.bmj.com
Objectives Both overall and central obesity have been associated with the risk of psoriasis in
a prospective study. Data on the association between obesity and psoriatic arthritis (PsA) …

T cell responses in psoriasis and psoriatic arthritis

M Diani, G Altomare, E Reali - Autoimmunity reviews, 2015 - Elsevier
According to the current view the histological features of psoriasis arise as a consequence of
the interplay between T cells, dendritic cells and keratinocytes giving rise to a self …