Background: The connection between uric acid (UA) and renal impairment is well known
due to the urate capacity to precipitate within the tubules or extra-renal system. Emerging …

Objective To review the epidemiology of gout and associated comorbidities. Methods We
review the key published studies of the epidemiology of gout and associated comorbidities …

Objective To estimate the current prevalence rates and decadal trends of gout and
hyperuricemia in the US, as well as the prevalence of urate‐lowering therapy (ULT) among …

Background New drugs and new evidence concerning the use of established treatments
have become available since the publication of the first European League Against …

Uric acid is the final product of purine metabolism, and its increased serum levels have been
directly involved in the pathogenesis and natural history of hypertension. The relationship …

The increased risk of cardiovascular morbidity and mortality in rheumatoid arthritis and gout
has been increasingly acknowledged in past decades, with accumulating evidence that …

Gout is the most common form of inflammatory arthritis and is a multifactorial disease
typically characterized by hyperuricemia and monosodium urate crystal deposition …

Gout is a common hyperuricaemic metabolic condition that leads to painful inflammatory
arthritis and a high comorbidity burden, especially cardiometabolic-renal (CMR) conditions …

Current blood-based approach for gout diagnosis can be of low sensitivity and hysteretic.
Here via a 68-member cohort of 33 healthy and 35 diseased individuals, we reported that …

Uric acid (UA) is the final product of purine metabolism in the human body, and impaired
purine metabolism can increase the uric acid in serum, finally resulting in hyperuricemia …