Polycystic ovary syndrome (PCOS) is increasingly recognized as a complex metabolic
disorder that manifests in genetically susceptible women following a range of negative …

The discovery and interpretation of peroxisome proliferator-activated receptor γ coactivator
1α (PGC-1α) protein in mitochondrial biogenesis, skeletal muscle and adipose tissue …

Abstract Purpose of Review Hypertriglyceridemia is a common dyslipidemia associated with
an increased risk of cardiovascular disease and pancreatitis. Severe hypertriglyceridemia …

Lipodystrophy syndromes (LDs) are characterized by loss of adipose tissue, metabolic
complications such as dyslipidemia, insulin resistance, and fatty liver disease, as well as …

Adipocytes are the primary sites for fatty acid storage, but the synthesis rate of fatty acids is
very low. The physiological significance of this phenomenon remains unclear. Here, we …

O-linked glycosylation, the greatest form of post-translational modifications, plays a key role
in regulating the majority of physiological processes. It is, therefore, not surprising that …

The prevalence of overweight and obesity continues to rise in the population worldwide.
Because it is an important predisposing factor for cancer, cardiovascular diseases, diabetes …

Introduction: Lipodystrophy (LD) syndromes are rare heterogeneous disorders characterized
by reduction or absence of subcutaneous fat, low or nondetectable leptin concentrations in …

Background: Lipodystrophy includes a wide group of diseases characterized by reduction,
absence, or altered distribution of adipose tissue. Lipodystrophies are classified into …

Adipocytes play a crucial role in the metabolism of lipids and sugars. Their response varies
depending on the circumstances or other factors influenced by physiological and metabolic …