Integration of systematic review, lipidomics with experiment verification reveals abnormal sphingolipids facilitate diabetes retinopathy by inducing oxidative stress on …

Z Yuan, Y Tian, C Zhang, M Wang, J Xie… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Objective This study aims to explore the potential biomarkers in the development of diabetes
mellitus (DM) into diabetes retinopathy (DR). Methods Systematic review of diabetic …

[HTML][HTML] Exploring the Prospective Role of Propolis in Modifying Aging Hallmarks

C Scorza, V Goncalves, J Finsterer, F Scorza… - Cells, 2024 - mdpi.com
Aging populations worldwide are placing age-related diseases at the forefront of the
research agenda. The therapeutic potential of natural substances, especially propolis and its …

Extraction, identification, and molecular mechanisms of α-glucosidase inhibitory peptides from defatted Antarctic krill (Euphausia superba) powder hydrolysates

K Zheng, Y Wu, Q Dai, X Yan, Y Liu, D Sun, Z Yu… - International Journal of …, 2024 - Elsevier
The objective of this study was to explore the potential of Antarctic krill-derived peptides as α-
glucosidase inhibitors for the treatment of type 2 diabetes. The enzymolysis conditions of α …

Study on the effect of licochalcone A on intestinal flora in type 2 diabetes mellitus mice based on 16S rRNA technology

Z Luo, J Xu, Q Gao, Z Wang, M Hou, Y Liu - Food & Function, 2023 - pubs.rsc.org
Licorice, has a long history in China where it has various uses, including as a medicine, and
is often widely consumed as a food ingredient. Licorice is rich in various active components …

Paeoniflorin ameliorates oxaliplatin-induced peripheral neuropathy via inhibiting neuroinflammation through influence on gut microbiota

J Xu, L Lu, S Jiang, Z Qin, J Huang, M Huang… - European Journal of …, 2024 - Elsevier
Oxaliplatin (OXA)-induced peripheral neuropathy (OIPN) is a severe side effect that greatly
limits OXA clinical use and threatens patients' life and health. Paeoniflorin exhibits extensive …

[HTML][HTML] Targeting metabolic pathways: a novel therapeutic direction for type 2 diabetes

Z Song, A Yan, Z Guo, Y Zhang, T Wen… - Frontiers in Cellular …, 2023 - ncbi.nlm.nih.gov
Background Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disease that causes
multi-organ complications, seriously affecting patients' quality of life and survival …

[HTML][HTML] Propolis from different Brazilian stingless bee species: phenolic composition and antimicrobial activity

VM Rocha, RW Portela, LE Lacerda… - … Processing and Nutrition, 2023 - Springer
Stingless bees (SLB) are insects bread many centuries ago by indigenous people and more
than 500 species have already been described. Interest in SLB's propolis has grown as a …

[HTML][HTML] Propolis Reduces Inflammation and Dyslipidemia Caused by High-Cholesterol Diet in Mice by Lowering ADAM10/17 Activities

E Yigit, O Deger, K Korkmaz, M Huner Yigit, HA Uydu… - Nutrients, 2024 - mdpi.com
Atherosclerosis is one of the most important causes of cardiovascular diseases. A disintegrin
and metalloprotease (ADAM) 10 and ADAM17 have been identified as important regulators …

From ancient wisdom to modern science: Gut microbiota sheds light on property theory of traditional Chinese medicine

Y Yang, J Zhan, Y Cao, C Wu - Journal of Integrative Medicine, 2024 - Elsevier
The property theory of traditional Chinese medicine (TCM) has been practiced for thousands
of years, playing a pivotal role in the clinical application of TCM. While advancements in …

[HTML][HTML] Exploratory studies on chrysin via antioxidant, antimicrobial, ADMET, PASS and molecular docking evaluations

AF Adesina, A Adewuyi, CA Otuechere - … Research-Modern Chinese …, 2024 - Elsevier
Introduction Chrysin, a flavonoid found in Feng Jiao (Chinese name for propolis), exhibits a
wide array of pharmacological activities and is recognized for the significant roles it plays in …