[HTML][HTML] Role of advanced glycation end products in cellular signaling
C Ott, K Jacobs, E Haucke, AN Santos, T Grune… - Redox biology, 2014 - Elsevier
Improvements in health care and lifestyle have led to an elevated lifespan and increased
focus on age-associated diseases, such as neurodegeneration, cardiovascular disease …
focus on age-associated diseases, such as neurodegeneration, cardiovascular disease …
Targeting the receptor for advanced glycation endproducts (RAGE): a medicinal chemistry perspective
S Bongarzone, V Savickas, F Luzi… - Journal of medicinal …, 2017 - ACS Publications
The receptor for advanced glycation endproducts (RAGE) is an ubiquitous, transmembrane,
immunoglobulin-like receptor that exists in multiple isoforms and binds to a diverse range of …
immunoglobulin-like receptor that exists in multiple isoforms and binds to a diverse range of …
RAGE: a single receptor fits multiple ligands
G Fritz - Trends in biochemical sciences, 2011 - cell.com
The receptor for advanced glycation end products (RAGE) is a central signaling molecule in
the innate immune system and is involved in the onset and sustainment of the inflammatory …
the innate immune system and is involved in the onset and sustainment of the inflammatory …
[HTML][HTML] RAGE in tissue homeostasis, repair and regeneration
RAGE (receptor for advanced glycation end-products) is a multiligand receptor of the
immunoglobulin superfamily involved in inflammation, diabetes, atherosclerosis …
immunoglobulin superfamily involved in inflammation, diabetes, atherosclerosis …
[PDF][PDF] Advanced glycation end product recognition by the receptor for AGEs
J Xue, V Rai, D Singer, S Chabierski, J Xie… - Structure, 2011 - cell.com
Nonenzymatic protein glycation results in the formation of advanced glycation end products
(AGEs) that are implicated in the pathology of diabetes, chronic inflammation, Alzheimer's …
(AGEs) that are implicated in the pathology of diabetes, chronic inflammation, Alzheimer's …
[PDF][PDF] Structural basis for ligand recognition and activation of RAGE
M Koch, S Chitayat, BM Dattilo, A Schiefner, J Diez… - Structure, 2010 - cell.com
The receptor for advanced glycation end products (RAGE) is a pattern recognition receptor
involved in inflammatory processes and is associated with diabetic complications, tumor …
involved in inflammatory processes and is associated with diabetic complications, tumor …
RAGE: therapeutic target and biomarker of the inflammatory response—the evidence mounts
R Ramasamy, SF Yan… - Journal of leukocyte …, 2009 - academic.oup.com
RAGE may be a biomarker and/or target for therapeutic intervention in chronic disease such
as diabetes, inflammation, neurodegeneration, and tumors. The RAGE binds multiple ligand …
as diabetes, inflammation, neurodegeneration, and tumors. The RAGE binds multiple ligand …
Advanced glycation end‐products and the kidney
M Busch, S Franke, C Rüster… - European journal of …, 2010 - Wiley Online Library
Eur J Clin Invest 2010; 40 (8): 742–755 Abstract Background Advanced glycation end‐
products (AGEs) are increased in situations with hyperglycemia and oxidative stress such as …
products (AGEs) are increased in situations with hyperglycemia and oxidative stress such as …
The receptor for advanced glycation end products (RAGE) specifically recognizes methylglyoxal-derived AGEs
Diabetes-induced hyperglycemia increases the extracellular concentration of methylglyoxal.
Methylglyoxal-derived hydroimidazolones (MG-H) form advanced glycation end products …
Methylglyoxal-derived hydroimidazolones (MG-H) form advanced glycation end products …
Soluble RAGE: therapy and biomarker in unraveling the RAGE axis in chronic disease and aging
SF Yan, R Ramasamy, AM Schmidt - Biochemical pharmacology, 2010 - Elsevier
The multi-ligand Receptor for Advanced Glycation Endproducts (RAGE) is implicated in the
pathogenesis and progression of chronic diseases such as diabetes and …
pathogenesis and progression of chronic diseases such as diabetes and …