Hydrogen sulfide (H 2 S) is an important signaling molecule in colorectal cancer (CRC). It is
produced in the colon by the catalytic synthesis of the colonocytes' enzymatic systems and …

Mitochondrial metabolism is an important contributor to cancer cell survival and proliferation
that coexists with enhanced glycolytic activity. Measuring mitochondrial activity is useful to …

Proofreading (editing) of mischarged tRNAs by cytoplasmic aminoacyl-tRNA synthetases
(aaRSs), whose impairment causes neurodegeneration and cardiac diseases, is of high …

Tamoxifen is the most commonly used treatment for estrogen-receptor (ER) positive breast
cancer patients, but its efficacy is severely hampered by resistance. PI3K/AKT/mTOR …

N-acetylcysteine (NAC) has been used as an antioxidant drug in tumor cells and preclinical
mice tumor xenografts, and it improves adaptive immunotherapy in melanoma. NAC is not …

Abstract STING (STimulator of Interferon Genes) is a cytosolic sensor for cyclic dinucleotides
(CDNs) and initiates an innate immune response upon binding to CDNs. Coxiella burnetii is …

Numerous chemical probes have been used to measure or image oxidative, nitrosative and
related stress induced by free radicals in biology and biochemistry. In many instances, the …

Simple Summary High-grade serous ovarian cancer (HGSOC) is the most prevalent type of
ovarian cancer, accounting for 70% of ovarian cancer deaths. This is primarily due to the …

Nanomedicine relies on the exploitation of nanoscale constructs for therapeutic and
diagnostic functions. Gold and gold–iron alloy nanoparticles (NPs) are two examples of …

In this review, we explore how short-chain fatty acids (SCFAs) produced by the gut
microbiome affect Parkinson's disease (PD) through their modulatory interactions with alpha …