Psychiatric patients have a greater risk of premature mortality, predominantly due to
cardiovascular diseases (CVDs). Convincing evidence shows that psychiatric conditions are …

People with serious mental illness (SMI), including schizophrenia, bipolar disorder, and
major depressive disorder, have a higher mortality rate and shortened life expectancy. This …

Observational studies suggested a bidirectional correlation between depression and
metabolic syndrome (MetS) and its components. However, the causal associations between …

Introduction The link between metabolic syndrome and depression has always been
controversial. Different studies that have examined the relationship between metabolic …

Schizophrenia (SCZ) and major depressive disorder (MDD) in treatment‐naive patients are
associated with increased risk for type 2 diabetes (T2D) and metabolic syndrome (MetS) …

Bipolar disorder (BD) has been associated with clinical signs of accelerated aging, which
potentially underlies its association with several age-related medical conditions, such as …

Objective The incidence of depression is significantly compounded by obesity. Obesity
arising from excessive intake of high-fat food provokes anxiodepressive behavior and elicits …

Dyslipidemia has been associated with depression, but individual lipid species associated
with depression remain largely unknown. The temporal relationship between lipid …

Depression is a major cause of morbidity and low quality of life among patients with
cardiovascular disease (CVD), and it is now considered as an independent risk factor for …

Peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1 alpha) is a
protein that regulates metabolism and inflammation by activating nuclear receptors …