Impact of impaired cholesterol homeostasis on neutrophils in atherosclerosis

B Tucker, J Ephraums, TW King, K Abburi… - … and Vascular Biology, 2023 - Am Heart Assoc
Atherosclerosis is complex chronic disease characterized by intimal cholesterol
accumulation and vascular inflammation. There is a well-established relationship of …

Extracellular vesicles mediate biological information delivery: A double-edged sword in cardiac remodeling after myocardial infarction

P Cheng, X Wang, Q Liu, T Yang, H Qu… - Frontiers in …, 2023 - frontiersin.org
Acute myocardial infarction (AMI) is a severe ischemic disease with high morbidity and
mortality worldwide. Maladaptive cardiac remodeling is a series of abnormalities in cardiac …

Neutrophil counts, neutrophil-to-lymphocyte ratio, and systemic inflammatory response index (SIRI) predict mortality after off-pump coronary artery bypass surgery

T Urbanowicz, M Michalak, A Olasińska-Wiśniewska… - Cells, 2022 - mdpi.com
Background: Several perioperative inflammatory markers are postulated to be significant
factors for long-term survival after off-pump coronary artery bypass surgery (OPCAB) …

Coronary No-Reflow after Primary Percutaneous Coronary Intervention—Current Knowledge on Pathophysiology, Diagnosis, Clinical Impact and Therapy

G Ndrepepa, A Kastrati - Journal of Clinical Medicine, 2023 - mdpi.com
Coronary no-reflow (CNR) is a frequent phenomenon that develops in patients with ST-
segment elevation myocardial infarction (STEMI) following reperfusion therapy. CNR is …

Exosomes of endothelial progenitor cells repair injured vascular endothelial cells through the Bcl2/Bax/Caspase-3 pathway

W Tan, Y Li, L Ma, X Fu, Q Long, F Yan, W Li, X Liu… - Scientific Reports, 2024 - nature.com
The main objective of this study is to evaluate the influence of exosomes derived from
endothelial progenitor cells (EPC-Exo) on neointimal formation induced by balloon injury in …

Circulating intermediate monocytes CD14++ CD16+ are increased after elective percutaneous coronary intervention

I Merinopoulos, U Bhalraam, T Holmes… - PLoS …, 2023 - journals.plos.org
Aim Inflammation plays a central role in the pathogenesis of atherosclerosis and in the
sequelae of percutaneous coronary intervention (PCI). Previous work demonstrated that …

Acute Coronary Syndromes (ACS)—Unravelling Biology to Identify New Therapies—The Microcirculation as a Frontier for New Therapies in ACS

K Vaidya, B Tucker, S Patel, MKC Ng - Cells, 2021 - mdpi.com
In acute coronary syndrome (ACS) patients, restoring epicardial culprit vessel patency and
flow with percutaneous coronary intervention or coronary artery bypass grafting has been …

[HTML][HTML] Ascophyllum nodosum and Fucus vesiculosus ameliorate restenosis via improving inflammation and regulating the PTEN/PI3K/AKT signaling pathway

CN Zumbi, CH Pan, HY Huang, CH Wu - Food Science and Human …, 2024 - Elsevier
Restenosis is a common complication following coronary angioplasty. The traditional use of
seaweeds for health benefits has increasingly been explored, however few studies exist …

Immediate versus staged complete revascularization in acute coronary syndrome: A meta-analysis of randomized controlled trials

K Bujak, R Rinaldi, P Vidal-Cales, RA Montone… - International Journal of …, 2023 - Elsevier
Background Clinical guidelines recommend a complete revascularization (CR) in patients
with acute coronary syndromes (ACS) and multivessel disease (MVD). However, its optimal …

Association between NLRP3 inflammasome and periprocedural myocardial injury following elective PCI

A Chen, D Lu, Z Yang, X Che, Y Xia, X Shao, Z Chen… - Heliyon, 2023 - cell.com
Background Periprocedural myocardial injury (PMI) is a common complication of
percutaneous coronary intervention (PCI) associated with poor prognosis. Inflammation has …