The novel CDK9 inhibitor, XPW1, alone and in combination with BRD4 inhibitor JQ1, for the treatment of clear cell renal cell carcinoma
Z Kuang, K Guo, Y Cao, M Jiang, C Wang… - British Journal of …, 2023 - nature.com
Background Clear cell renal cell carcinoma (ccRCC) is a highly lethal malignancy with few
therapeutic options. Cyclin‑dependent kinase 9 (CDK9), a potential therapeutic target of …
therapeutic options. Cyclin‑dependent kinase 9 (CDK9), a potential therapeutic target of …
Study on the active ingredients and mechanism of action of Jiaotai Pill in the treatment of type 2 diabetes based on network pharmacology: A review
X Chen, Z Yang, L Du, Y Guan, Y Li, C Liu - Medicine, 2023 - journals.lww.com
To explore the potential active ingredients and related mechanisms of Jiaotai Pill in the
treatment of Type 2 diabetes mellitus (T2DM) based on network pharmacology and …
treatment of Type 2 diabetes mellitus (T2DM) based on network pharmacology and …
[HTML][HTML] Hyperuricemia contributes to glucose intolerance of hepatic inflammatory macrophages and impairs the insulin signaling pathway via IRS2-proteasome …
H Zhao, J Lu, F He, M Wang, Y Yan, B Chen… - Frontiers in …, 2022 - frontiersin.org
Aim Numerous reports have demonstrated the key importance of macrophage-elicited
metabolic inflammation in insulin resistance (IR). Our previous studies confirmed that …
metabolic inflammation in insulin resistance (IR). Our previous studies confirmed that …
The role of snapin in regulation of brain homeostasis
J Li, X Huang, Y An, X Chen, Y Chen… - Neural Regeneration …, 2024 - journals.lww.com
Brain homeostasis refers to the normal working state of the brain in a certain period, which is
important for overall health and normal life activities. Currently, there is a lack of effective …
important for overall health and normal life activities. Currently, there is a lack of effective …
Snapin 蛋白在调节脑稳态中的作用
J Li, X Huang, Y An, X Chen, Y Chen, M Xu… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
脑稳态是指大脑在一定时间内的正常工作状态, 对于人体的健康和正常生命活动具有重要意义.
目前针对脑稳态失调所带来的不良后果, 尚缺乏有效的治疗方法. 近期, 许多研究人员报道snapin …
目前针对脑稳态失调所带来的不良后果, 尚缺乏有效的治疗方法. 近期, 许多研究人员报道snapin …
[引用][C] Study on the active ingredients and mechanism of action of Jiaotai Pill in the treatment of type 2 diabetes based on network pharmacology
MM Xiaona Chen, MM Zhao Yang, MM Lin Du… - 2023 - europepmc.org
To explore the potential active ingredients and related mechanisms of Jiaotai Pill in the
treatment of Type 2 diabetes mellitus (T2DM) based on network pharmacology and …
treatment of Type 2 diabetes mellitus (T2DM) based on network pharmacology and …